Synthesis of thioesters by simultaneous activation of carboxylic acids and alcohols using PPh3/NBS with benzyltriethylammonium tetrathiomolybdate as the sulfur …

…, RS Vidyarini, S Chandrasekaran

Index: Gopinath, Purushothaman; Vidyarini, Ravindran Sasitha; Chandrasekaran, Srinivasan European Journal of Organic Chemistry, 2009 , # 34 p. 6043 - 6047

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Citation Number: 7

Abstract

Abstract A new and simple route for the synthesis of thioesters starting from carboxylic acids and alcohols is reported by using tetrathiomolybdate as the key sulfur transfer reagent. Triphenylphosphane and N-bromosuccinimide were used for the activation of the carboxylic acid and alcohol in the same pot followed by the transfer of sulfur from tetrathiomolybdate. Thioesters were obtained in good to moderate yields. Primary alcohols show excellent ...