As a continuation of our structure-activity relationship study of substituted 2-phenyl-4- quinolones and flavonoids as antitumor and antiviral agents, a series of 5, 6, 7, 8-substituted- 2-phenylthiochromen-4-ones has been synthesized by condensation of substituted thiophenols and ethyl benzoylacetates. Target compounds were evaluated for biological activity. Among them, compounds 7, 10, 12, and 13 displayed significant growth inhibitory ...
