e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Non-template synthesis of 'N 4'macrocyclic imine ligands with variable ring sizes: the importance of intramolecular hydrogen-bonding. X-Ray crystal structures of three …
…, R Peters, E Ramsammy, PA Tasker, J Trotter
Index: Owston, Philip G.; Peters, Roger; Ramsammy, Edward; Tasker, Peter A.; Trotter, Jill Journal of the Chemical Society, Chemical Communications, 1980 , # 24 p. 1218 - 1220
Di-imine tetra-aza macrocycles with an extensive range of ring sizes can be isolated by simple condensations without recourse to 'metal-ion template'or 'high-dilution'reactions, provided the rings can form intramolecular hydrogen bonds to reduce unfavourable lone- pair–lone-pair interactions between the nitrogen atoms.
