Sarkomycin is known to display a powerful inhibitory effect on Ehrlich ascites tumors in mice. 1 As a result of the biological activities associated with sarkomycin and some analogues, among them homosarkomycin, 2., and many syntheses of these targets have been reported as multi-step syntheses 3., , , 4., 5., , and with low overall yields. We have previously described a short large-scale synthesis of (±)-sarkomycin esters 6 and derivatives 7 including a cyclic ...
