Synthesis of Schiff bases from 3-amino-3-arylpropionic acid esters in aqueous medium

NN Romanova, II Rybalko, TG Tallo, NV Zyk…

Index: Romanova; Rybalko; Tallo; Zyk; Svedas Russian Journal of Organic Chemistry, 2012 , vol. 48, # 6 p. 860 - 863

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Abstract

Schiff bases constitute one of the most thoroughly studied and practically important class of organic compounds. Their biological activity is well known. Some Schiff bases inhibit many enzymes [1–8] and possess bactericidal [9, 10], fungicidal [11, 12], herbicidal,[13] and anticancer activity [14, 15]. Schiff bases had been used in organic synthesis since 1907 when Staudinger reported on their reaction with ketenes [16]. At present Schiff bases are ...