Canadian Journal of Chemistry

Twofold alkylations of ketone and aldehyde phenylhydrazones with methylene halides by means of alkali amides to form bis-N-derivatives

FE Henoch, CR Hauser

Index: Henoch,F.E.; Hauser,C.R. Canadian Journal of Chemistry, 1969 , vol. 47, p. 157 - 160

Full Text: HTML

Citation Number: 6

Abstract

The phenylhydrazones of benzophenone, acetophenone, and benzaldehyde were converted by a molecular equivalent of an alkali amide in liquid ammonia to their mono- alkali derivatives, which underwent twofold alkylation with 1, 3-dibromopropane or higher methylene halides or with α, α'-dichloro-p-xylene to form corresponding bis-N-derivatives. Two of the products were reduced by means of lithium in liquid ammonia to give ...