Tetrahedron letters

Pseudomonas cepacia lipase mediated amidation of benzyl esters

M Adamczyk, J Grote

Index: Adamczyk, Maciej; Grote, Jonathan Tetrahedron Letters, 1996 , vol. 37, # 44 p. 7913 - 7916

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Citation Number: 21

Abstract

Although lipases have been known for some time as catalysts useful for regioselective transesterification or hydrolysis, studies regarding their use as ester amidation catalysts are limited. We have found that the lipase from Pseudomonas cepacia catalyzes amidation reactions with benzyl esters, producing high yields of amides with a variety of different amines.