Biological studies of photoinducible phenol quaternary ammonium derivatives

…, P Wang, J Wu, X Zhou, XL Zhang, L Weng…

Index: Song, Yang; Wang, Ping; Wu, Juanjuan; Zhou, Xiang; Zhang, Xiao-Lian; Weng, Linhong; Cao, Xiaoping; Liang, Feng Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 6 p. 1660 - 1664

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Citation Number: 15

Abstract

Three water-soluble DNA cross-linking phenol quaternary ammonium derivatives 3, 4, and 5 could inhibit the transcription in vitro by photoactivation. DNA interstrand cross-linking action might be the key factor to inhibit transcription by these compounds. Further tumor cell ...