Previous studies in these laboratories have demonstrated that certain compounds containing 2, 2-dimethylpyrrolidiiie (I) are particularly potent anticholinergics. The structurally similar compound, l-azaspiro [4.5] decane (11), has now been prepared, in which the two methyl groups are joined in a ring. This was incorporated into a variety of compounds of types known to be ill general powerful anticholinergics (VIII, IX and XI); however, they had ...
![4-(1-methyl-1-azoniaspiro[4.5]dec-1-yl)-2,2-diphenyl-butanamide Structure](https://image.chemsrc.com/caspic/209/5421-65-8.png)
![4-(1-aza-spiro[4.5]dec-1-yl)-2,2-diphenyl-butyric acid amide Structure](https://image.chemsrc.com/caspic/047/114400-06-5.png)