Journal of Medicinal Chemistry

Aldehyde hydrazone derivatives in cancer chemotherapy

RH Wiley, RL Clevenger

Index: Wiley,R.H.; Clevenger,R.L. Journal of Medicinal and Pharmaceutical Chemistry, 1962 , vol. 5, p. 1367 - 1371

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Citation Number: 29

Abstract

" The following procedures were used in the preparations: I. To 3.75 g.(0.02 mole) of 2- methoxy-1-naphthaldehyde [N. Ph. Buu-Hoi and D. Lavit, J. Chem. Soc, 2776 (1955)] in 25 mi of hot methanol was added a warm aqueous solution of the appropriate hydrazine. Glacial acetic acid (10 nil.) was added The reaction mixture was~ arnied to boiling and then cooled in an ice bath. The product mas collected on a filter and recrystallized. 11. To a ...