Pd (II)-Catalyzed Hydroxyl-Directed C− H Activation/C− O Cyclization: Expedient Construction of Dihydrobenzofurans

X Wang, Y Lu, HX Dai, JQ Yu

Index: Wang, Xisheng; Lu, Yi; Dai, Hui-Xiong; Yu, Jin-Quan Journal of the American Chemical Society, 2010 , vol. 132, # 35 p. 12203 - 12205

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Citation Number: 189

Abstract

A Pd (II)-catalyzed C− H activation/C− O cyclization reaction directed by a proximate hydroxyl group has been developed. This reaction provides a new method for constructing dihydrobenzofurans, including spirocyclic analogues, a process that is potentially applicable to natural product synthesis.