Tetrahedron

Sequenced elimination–reduction and elimination–cyclopropanation reactions of 2, 3-epoxyamides promoted by samarium diiodide. Synthesis of 2, 3- …

JM Concellón, M Huerta, E Bardales

Index: Concellon, Jose M.; Huerta, Monica; Bardales, Eva Tetrahedron, 2004 , vol. 60, # 44 p. 10059 - 10065

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Citation Number: 11

Abstract

An easy and general sequenced elimination/reduction or elimination/cyclopropanation process promoted by samarium diiodide or/and CH2I2/Sm provide an efficient method for synthesising 2, 3-dideuterioamides or cyclopropanamides, respectively. The transformations take place in high yields and with total or high selectivity from the easily available 2, 3- epoxyamides.