Synthetic communications

Superacid-Promoted Hydroxyalkylation of 1, 2-Indandiones

AF Tracy, MP Abbott, DA Klumpp

Index: Tracy, Adam F.; Abbott, Matthew P.; Klumpp, Douglas A. Synthetic Communications, 2013 , vol. 43, # 16 p. 2171 - 2177

Full Text: HTML

Citation Number: 3

Abstract

1,2-Indandione reacts efficiently with arenes to give 2,2-diaryl-1-indanones by the hydroxyalkylation reaction. The Brønsted superacid CF 3 SO 3 H (triflic acid) is an effective catalyst for these condensation reactions. The requisite 1,2-indandiones were prepared from the 1-indanones. ... 1,2-Indandione reacts efficiently with arenes to give 2,2-diaryl-1-indanones by the hydroxyalkylation reaction. The Brønsted superacid CF 3 SO 3 H (triflic acid) is an effective catalyst for these ...