Tetrahedron Letters

Efficient synthesis of indenes by FeCl 3· 6H 2 O-catalyzed intramolecular Friedel–Crafts reaction of aryl-substituted allylic alcohols

J Wang, L Zhang, Y Jing, W Huang, X Zhou

Index: Wang, Jialiang; Zhang, Lixin; Jing, Yufeng; Huang, Wen; Zhou, Xigeng Tetrahedron Letters, 2009 , vol. 50, # 35 p. 4978 - 4982

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Citation Number: 48

Abstract

An efficient procedure for the synthesis of substituted indenes through the FeCl3· 6H2O- catalyzed intramolecular Friedel–Crafts cyclization of aryl-substituted allylic alcohols has been developed. This method features the easily available starting materials, cheap catalyst, simple manipulation, and mild conditions.