The Journal of Organic Chemistry

Relative Reactivity in Piperidino-Dechlorination of 2, 4-Diamino-6-chloropyrimidine and 2, 4-Diamino-6-chloropyrimidine N (3)-Oxide and Their Acetylamino Analogs

M Maltese

Index: Maltese, M. Journal of Organic Chemistry, 1995 , vol. 60, # 8 p. 2436 - 2442

Full Text: HTML

Citation Number: 2

Abstract

The second-order rate constants k A for the piperidino-dechlorination of 2, 4-diamino-6- chloropyri-midine (la), 2, 4-bis (acetylamino)-6-chloropyrimidine (lb), 2, 4-diamino-6- chloropyrimidine N (3)-oxide (2a), and 2, 4-bis (acetylamino)-6-chloropyrimidine N (3)-oxide (2b) have been determined from the corresponding pseudo-first-order rate constants, AI), measured in DMSO at 21.0" C by the UV spectrophotometric procedure. The second-order ...