5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid monohydrate
5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid monohydrate structure
|
Common Name | 5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid monohydrate | ||
|---|---|---|---|---|
| CAS Number | 190908-40-8 | Molecular Weight | 276.07300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H7Cl2NO4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
[3H]5,7-dichlorokynurenic acid, a novel radioligand labels NMDA receptor-associated glycine binding sites.
Eur. J. Pharmacol. 206 , 149, (1991) A strychnine-insensitive glycine binding site is located on the N-methyl-D-aspartate (NMDA)-preferring glutamate receptor complex. Kynurenic acid analogs are antagonists at this binding site. A derivative of kynurenic acid, 5,7-dichlorokynurenic acid (5,7-DCK... |
|
|
Activity of 5,7-dichlorokynurenic acid, a potent antagonist at the N-methyl-D-aspartate receptor-associated glycine binding site.
Mol. Pharmacol. 38 , 554, (1990) 5,7-Dichlorokynurenic acid (5,7-DCKA), one of the most potent excitatory amino acid receptor antagonists yet described, binds to a strychnine-insensitive glycine binding site located on the N-methyl-D-aspartate (NMDA) receptor complex (Ki = 79 nM versus [3H]g... |
Journals:
More...