奥美拉唑砜结构式
|
常用名 | 奥美拉唑砜 | 英文名 | Omeprazole Sulfone |
|---|---|---|---|---|
| CAS号 | 88546-55-8 | 分子量 | 361.415 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 599.3±60.0 °C at 760 mmHg | |
| 分子式 | C17H19N3O4S | 熔点 | 80-82ºC | |
| MSDS | 中文版 美版 | 闪点 | 316.2±32.9 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
奥美拉唑砜用途Omeprazole sulfone是Omeprazole的代谢物。 |
| 中文名 | 奥美拉唑杂质A |
|---|---|
| 英文名 | 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfonyl]-1H-benzimidazole |
| 中文别名 | 埃索美拉唑EP杂质D | 奥美拉唑杂质 D | 奥美拉唑砜 |
| 英文别名 | 更多 |
| 密度 | 1.3±0.1 g/cm3 |
|---|---|
| 沸点 | 599.3±60.0 °C at 760 mmHg |
| 熔点 | 80-82ºC |
| 分子式 | C17H19N3O4S |
| 分子量 | 361.415 |
| 闪点 | 316.2±32.9 °C |
| 精确质量 | 361.109619 |
| PSA | 102.55000 |
| LogP | 3.87 |
| 蒸汽压 | 0.0±1.7 mmHg at 25°C |
| 折射率 | 1.609 |
| 储存条件 | -20°C Freezer |
| 符号 |
GHS07 |
|---|---|
| 信号词 | Warning |
| 危害声明 | H315-H319-H335 |
| 警示性声明 | P261-P305 + P351 + P338 |
| 危害码 (欧洲) | Xi |
| 风险声明 (欧洲) | 36/37/38 |
| 安全声明 (欧洲) | 26-36 |
| 危险品运输编码 | NONH for all modes of transport |
| 海关编码 | 2933990090 |
| 海关编码 | 2933990090 |
|---|---|
| 中文概述 | 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期 |
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Pharmacokinetics of omeprazole and its metabolites in three phases of menstrual cycle.
Eur. J. Drug Metab. Pharmacokinet. 40(1) , 13-22, (2015) Omeprazole (OMP) is effective in the treatment of gastric hyperacidity and is metabolized by CYP2C19 and CYP3A4. These enzymes are modulated by estrogen and progesterone which regulate the menstrual c... |
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CYP2C19 haplotypes in Koreans as a marker of enzyme activity evaluated with omeprazole.
J. Clin. Pharm. Ther. 34(4) , 437-46, (2009) CYP2C19 is clinically important in Korea because of the relatively high incidence of poor metabolizers in the population. To fully understand the genetic mechanism of the CYP2C19 defect in poor metabo... |
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Metabolism of omeprazole after two oral doses in children 1 to 9 months old.
Proc. West. Pharmacol. Soc. 48 , 108-9, (2005) Essential oils from onion (Allium cepa L.), garlic (Allium sativum L.), and their main components, such as propyl thiosulfinate oxide (PTSO) are being intended for active packaging with the purpose of... |
| 1H-Benzimidazole,6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl] |
| Omeprazole sulfone |
| 5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfonyl)-1H-benzo[d]imidazole |
| 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]- |
| Omeprazole sulphone |
| BEN501 |
| 5-Methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfonyl}-1H-benzimidazole |
| 5-Methoxy-2-{[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl}-1H-benzimidazole |
| Esomeprazole Impurity 4 |
| Omeprazole metabolite Omeprazole sulfone |
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