黄芪皂苷II

• 常用名: 黄芪皂苷II
• 英文名: Astragaloside II
• CAS号: 84676-89-1
• 分子量: 827.01
• 密度: 1.4±0.1 g/cm3
• 沸点: 896.9±65.0 °C at 760 mmHg
• 分子式: C₄₃H₇₀O₁₅
• 熔点: N/A
• 闪点: 265.3±27.8 °C

黄芪皂苷II用途

黄芪皂苷II (Astragaloside II) 是从黄芪中分离到的一种天然化合物。

黄芪皂苷II名称

• 中文名: 黄芪皂苷 II
• 英文名: Astragaloside II
• 中文别名: 黄芪皂苷-Ⅱ | 黄芪皂苷II

黄芪皂苷II生物活性

• 描述: 黄芪皂苷II (Astragaloside II) 是从黄芪中分离到的一种天然化合物。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他
  天然产物 >> 萜类化合物和糖苷
• 参考文献:

  [1]. Haijun Qu, et al. Quantification and pharmacokinetics of astragaloside II in rats by rapid liquid chromatography-tandem mass spectrometry. Anal. Methods, 2014,6, 6815-6822

  [2]. Kong XH, et al. Astragaloside II induces osteogenic activities of osteoblasts through the bone morphogenetic protein-2/MAPK and Smad1/5/8 pathways. Int J Mol Med. 2012 Jun;29(6):1090-8.

  [3]. Huang C, et al. Reversal of P-glycoprotein-mediated multidrug resistance of human hepatic cancer cells by Astragaloside II. J Pharm Pharmacol. 2012 Dec;64(12):1741-50.

  [4]. Wan CP, et al. Astragaloside II triggers T cell activation through regulation of CD45 protein tyrosine phosphatase activity. Acta Pharmacol Sin. 2013 Apr;34(4):522-30.

黄芪皂苷II物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 896.9±65.0 °C at 760 mmHg
• 分子式: C₄₃H₇₀O₁₅
• 分子量: 827.01
• 闪点: 265.3±27.8 °C
• PSA: 234.29000
• LogP: 0.80
• InChIKey: AYWNHWGQTMCQIV-RHKAXKFRSA-N
• SMILES: CC(=O)OC1C(OC2CCC34CC35CCC3(C)C(C6(C)CCC(C(C)(C)O)O6)C(O)CC3(C)C5CC(OC3OC(CO)C(O)C(O)C3O)C4C2(C)C)OCC(O)C1O
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.615
• 储存条件: 室温

黄芪皂苷II安全信息

• 危害码 (欧洲): Xi
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 29389090

黄芪皂苷II英文别名

• β-D-Glucopyranoside, (3β,6α,16β,20R,24S)-3-[(2-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-14-methyl-9,19-cyclocholestan-6-yl
• Cyclosieversioside D
• (3β,6α,16β,20R,24S)-3-[(2-O-Acetyl-β-D-xylopyranosyl)oxy]-16,25-dihydroxy-14-methyl-20,24-epoxy-9,19-cyclocholestan-6-yl β-D-glucopyranoside
• AstrasieversianinVIII
• 16,25-dihydroxy-9,19-cyclolanostan-6-yl
• Astragaloside B
• Cyclosiversioside D