头孢呋辛钠EP杂质A

• 常用名: 头孢呋辛钠EP杂质A
• 英文名: Descarbamoyl Cefuroxime
• CAS号: 56271-94-4
• 分子量: 381.36100
• 密度: 1.72g/cm3
• 沸点: N/A
• 分子式: C₁₅H₁₅N₃O₇S
• 熔点: N/A
• 闪点: N/A

头孢呋辛钠EP杂质A用途

Descarbamoyl cefuroxime 是 Cefuroxime 的降解产物。Descarbamoyl cefuroxime 是头孢菌素类抗生素合成的中间体。

头孢呋辛钠EP杂质A名称

• 中文名: 头孢呋辛钠EP杂质A
• 英文名: 7-{[2-Furyl(methoxyimino)acetyl]amino}-3-(hydroxymethyl)-8-oxo-5- thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

头孢呋辛钠EP杂质A生物活性

• 描述: Descarbamoyl cefuroxime 是 Cefuroxime 的降解产物。Descarbamoyl cefuroxime 是头孢菌素类抗生素合成的中间体。
• 相关类别:
  研究领域 >> 感染
• 参考文献:

  [1]. Vercheval C, et al. Stability of 90 mg/mL cefuroxime sodium solution for administration by continuous infusion. J Chemother. 2018 Oct - Dec;30(6-8):371-374.

  [2]. Takaya T, et al. Studies on beta-lactam antibiotics. III. Synthesis and enzymatic stability of 3-acyloxymethyl-7 beta-[(Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-cephem-4-carboxylic acids. J Antibiot (Tokyo). 1981 Oct;34(10):1300-10.

头孢呋辛钠EP杂质A物理化学性质

• 密度: 1.72g/cm3
• 分子式: C₁₅H₁₅N₃O₇S
• 分子量: 381.36100
• 精确质量: 381.06300
• PSA: 170.46000
• LogP: 0.13920
• InChIKey: OUSLHGWWWMRAIG-FBCAJUAOSA-N
• SMILES: CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CO)CSC12)c1ccco1
• 折射率: 1.733

头孢呋辛钠EP杂质A英文别名

• 7-PHENYLACETAMIDE-3-CHLOROMETHYL-CEPHALOSPORANIC ACID P-METHOXYBENZYL ESTER
• Descarbamoyl Cefuroxime
• GCLE:INTERMEDIATE FOR CEPHALOSPORIN
• 3-chloromethyl-7-phenylacetylaminocephalosporanic acid p-methoxybenzyl ester
• 7-PHENYLACETAMIDO-3-CHLOROMETHYLCEPHEM-4-CARBONICACID-PARA-METHOXYBENZYLESTER
• 7-phenylacetamido-3-chloromethylcephem-4-carbonicacidp-methoxybenzylester
• 7-PHENYLACETAMINO-3-CHLOROMETHYL-3-CEPHEM4-CARBOXYLIC ACID P-METHOXYBENZYL ESTER
• Cefuroxime Impurity 4