4-氧代-维A酸结构式
|
常用名 | 4-氧代-维A酸 | 英文名 | all-trans-4-Oxoretinoic acid |
|---|---|---|---|---|
| CAS号 | 38030-57-8 | 分子量 | 314.41900 | |
| 密度 | 1.07g/cm3 | 沸点 | 509.9ºC at 760 mmHg | |
| 分子式 | C20H26O3 | 熔点 | 175-178°C (分解) | |
| MSDS | N/A | 闪点 | 276.3ºC |
4-氧代-维A酸用途all-trans-4-Oxoretinoic acid,是维生素A 的活性代谢物,可通过作用核维甲酸受体 (RARs) 来诱导基因转录。 |
| 中文名 | 4-氧代-维A酸 |
|---|---|
| 英文名 | all-trans-4-oxoretinoic acid |
| 中文别名 | 4-氧代-全反式维甲酸 | 3,7-二甲基-9-(4-氧代-2,6,6-三甲基环己烯)-2,4,6,8-全反式壬四烯酸 | 4-氧代-视黄酸 | 维A酸-4-酮 |
| 英文别名 | 更多 |
| 描述 | all-trans-4-Oxoretinoic acid,是维生素A 的活性代谢物,可通过作用核维甲酸受体 (RARs) 来诱导基因转录。 |
|---|---|
| 相关类别 | |
| 靶点 |
Human Endogenous Metabolite |
| 体外研究 | 全反式-4-氧代氨基酸,维生素A的活性代谢产物,通过与核视黄酸受体(RARs)的结合诱导基因转录[1]。全反式-4-氧代氨基酸是视黄酸(RA)的生物活性几何异构体[2]。 |
| 参考文献 |
| 密度 | 1.07g/cm3 |
|---|---|
| 沸点 | 509.9ºC at 760 mmHg |
| 熔点 | 175-178°C (分解) |
| 分子式 | C20H26O3 |
| 分子量 | 314.41900 |
| 闪点 | 276.3ºC |
| 精确质量 | 314.18800 |
| PSA | 54.37000 |
| LogP | 4.78160 |
| 折射率 | 1.565 |
| 储存条件 | 2-8℃ |
|
~87%
4-氧代-维A酸 38030-57-8 |
| 文献：Mironova; Leont'eva; Shevyakov; Alexeeva; Shvets; Demina; Krasnokutskaya; Finkel'shtein; Khodonov Russian Journal of Bioorganic Chemistry, 2002 , vol. 28, # 6 p. 487 - 493 |
|
~%
4-氧代-维A酸 38030-57-8 |
| 文献：Rosenberger Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1698 - 1701 |
|
~%
4-氧代-维A酸 38030-57-8 |
| 文献：Rosenberger Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1698 - 1701 |
|
~%
4-氧代-维A酸 38030-57-8 |
| 文献：Aig, Edward; Focella, Antonino; Parrish, David R.; Rosenberger, Michael; Scott, John W.; Zenchoff, Gladys B. Synthetic Communications, 1987 , vol. 17, # 4 p. 419 - 430 |
|
~%
4-氧代-维A酸 38030-57-8 |
| 文献：Aig, Edward; Focella, Antonino; Parrish, David R.; Rosenberger, Michael; Scott, John W.; Zenchoff, Gladys B. Synthetic Communications, 1987 , vol. 17, # 4 p. 419 - 430 |
|
~%
4-氧代-维A酸 38030-57-8 |
| 文献：UNIVERSITY OF WASHINGTON Patent: US2008/249042 A1, 2008 ; Location in patent: Page/Page column 2; 27; 29; 31; Sheet 14/24; 24/24 ; |
|
~%
4-氧代-维A酸 38030-57-8 |
| 文献：Mironova; Leont'eva; Shevyakov; Alexeeva; Shvets; Demina; Krasnokutskaya; Finkel'shtein; Khodonov Russian Journal of Bioorganic Chemistry, 2002 , vol. 28, # 6 p. 487 - 493 |
|
~%
4-氧代-维A酸 38030-57-8 |
| 文献：Rosenberger Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1698 - 1701 |
|
~%
4-氧代-维A酸 38030-57-8 |
| 文献：Aig, Edward; Focella, Antonino; Parrish, David R.; Rosenberger, Michael; Scott, John W.; Zenchoff, Gladys B. Synthetic Communications, 1987 , vol. 17, # 4 p. 419 - 430 |
| 4-氧代-维A酸上游产品 9 | |
|---|---|
| 4-氧代-维A酸下游产品 1 | |
| 4-keto-Retinoic Acid |
| 4-oxo-all-rans-retinoic acid |
| 4-Oxoretinoic Acid |
| all-trans-4-Oxoretinoic Acid |
| 4-oxo-all-trans-retinoic acid |
| all-trans 4-Keto Retinoic Acid |
| 4-oxo-Retinoic acid |
| 4-Ketoretinoic Acid |
| 4-Oxo-atRA |
| 4-Oxotretinoin |
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