LB42908

• 常用名: LB42908
• 英文名: LB42908
• CAS号: 226927-89-5
• 分子量: 533.62000
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₂H₃₁N₅O₃
• 熔点: N/A
• 闪点: N/A

LB42908用途

LB42908 is a highly potent, selective, orally active inhibitor of Ras farnesyltransferase (FTase) with IC50 of 0.9 nM against H-Ras and 2.4 nM against K-Ras..

LB42908名称

• 英文名: [1-{[1-(1,3-benzodioxole-5-ylmethyl)-1H-imidazole-5-yl]methyl}-4-(1-naphthyl)-1H-pyrrole-3yl](4-methyl-1-piperazinyl)methanone

LB42908物理化学性质

• 分子式: C₃₂H₃₁N₅O₃
• 分子量: 533.62000
• 精确质量: 533.24300
• PSA: 64.76000
• LogP: 4.59350
• InChIKey: HWLBLFBLGGVDBT-UHFFFAOYSA-N
• SMILES: CN1CCN(C(=O)c2cn(Cc3cncn3Cc3ccc4c(c3)OCO4)cc2-c2cccc3ccccc23)CC1

LB42908英文别名

• LB-42908
• 1-[1-(3,4-methylenedioxybenzyl)-1H-imidazol-5-ylmethyl]-3-(4-methylpiperazin-1-yl)carbonyl-4-(naphthalen-1-yl)-1H-pyrrole
• 1-[1-(3,4-methylenedioxybenzyl)-1H-imidazol-5-ylmethyl]-3-(4methylpiperazin-1-yl)carbonyl-4(naphthalen-1-yl)-1H-pyrrole