7-表-10-氧-多西他赛(多西他赛杂质D)

• 常用名: 7-表-10-氧-多西他赛(多西他赛杂质D)
• 英文名: 7-Epi-10-oxo-docetaxel
• CAS号: 162784-72-7
• 分子量: 805.86300
• 密度: 1.4±0.1 g/cm3
• 沸点: 887.3±65.0 °C at 760 mmHg
• 分子式: C₄₃H₅₁NO₁₄
• 熔点: N/A
• 闪点: 490.4±34.3 °C

7-表-10-氧-多西他赛(多西他赛杂质D)用途

7-Epi-10-oxo-docetaxel (Docetaxel Impurity D)是多西他赛(docetaxel)的杂质。

7-表-10-氧-多西他赛(多西他赛杂质D)名称

• 中文名: 7-表-10-氧代-多西他赛
• 英文名: (2α,5β,7α,13α)-4-Acetoxy-1,7-dihydroxy-13-{[(2R,3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-9,10-dioxo-5,20-epoxytax-11-en-2-yl benzoate

7-表-10-氧-多西他赛(多西他赛杂质D)生物活性

• 描述: 7-Epi-10-oxo-docetaxel (Docetaxel Impurity D)是多西他赛(docetaxel)的杂质。
• 相关类别:
  信号通路 >> 细胞周期/DNA损伤 >> 微管/微管蛋白
  信号通路 >> 细胞骨架 >> 微管/微管蛋白
  研究领域 >> 癌症
• 参考文献:

  [1]. Vasu Dev R, et al. Isolation and characterization of impurities in docetaxel. J Pharm Biomed Anal. 2006 Feb 24;40(3):614-22.

7-表-10-氧-多西他赛(多西他赛杂质D)物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 887.3±65.0 °C at 760 mmHg
• 分子式: C₄₃H₅₁NO₁₄
• 分子量: 805.86300
• 闪点: 490.4±34.3 °C
• 精确质量: 805.33100
• PSA: 224.78000
• LogP: 6.29
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.614
• 储存条件: 2-8℃

7-表-10-氧-多西他赛(多西他赛杂质D)英文别名

• (2b,5b,7a,13a)-4-Acetoxy-13-(((2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl)oxy)-1,7-dihydroxy-9,10-dioxo-5,20-epoxytax-11-en-2-yl Benzoate
• (2α,5β,7α,13α)-4-Acetoxy-1,7-dihydroxy-13-{[(2R,3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-9,10-dioxo-5,20-epoxytax-11-en-2-yl benzoate
• 7-Epi-10-oxo-docetaxel
• Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4R,4aS,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-di hydroxy-4a,8,13,13-tetramethyl-5,6-dioxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
• UNII-23YRN771SO