缬沙坦苄酯结构式
|
常用名 | 缬沙坦苄酯 | 英文名 | Valsartan benzyl ester |
|---|---|---|---|---|
| CAS号 | 137863-20-8 | 分子量 | 525.641 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 720.1±70.0 °C at 760 mmHg | |
| 分子式 | C31H35N5O3 | 熔点 | >71° C(dec.) | |
| MSDS | N/A | 闪点 | 389.3±35.7 °C |
缬沙坦苄酯用途Valsartan benzyl ester is a Valsartan intermediate. |
| 中文名 | 缬沙坦苄酯 |
|---|---|
| 英文名 | (S)-Benzyl 2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate |
| 中文别名 | 缬沙坦相关物质C | 缬沙坦杂质B |
| 英文别名 | 更多 |
| 密度 | 1.2±0.1 g/cm3 |
|---|---|
| 沸点 | 720.1±70.0 °C at 760 mmHg |
| 熔点 | >71° C(dec.) |
| 分子式 | C31H35N5O3 |
| 分子量 | 525.641 |
| 闪点 | 389.3±35.7 °C |
| 精确质量 | 525.273987 |
| PSA | 101.07000 |
| LogP | 7.16 |
| 蒸汽压 | 0.0±2.3 mmHg at 25°C |
| 折射率 | 1.589 |
| 储存条件 | 室温 |
| 危害码 (欧洲) | Xn |
|---|
|
~90%
缬沙坦苄酯 137863-20-8 |
| 文献:ENANTIA, S. L. Patent: WO2006/67216 A2, 2006 ; Location in patent: Page/Page column 29 ; WO 2006/067216 A2 |
|
~%
缬沙坦苄酯 137863-20-8 |
| 文献:WO2005/49588 A1, ; Page/Page column 6 ; |
|
~%
缬沙坦苄酯 137863-20-8 |
| 文献:WO2004/26847 A1, ; Page 26; 32-33 ; WO 2004/026847 A1 |
|
~0%
缬沙坦苄酯 137863-20-8 |
| 文献:ZENTIVA, a.s. Patent: WO2005/21535 A2, 2005 ; Location in patent: Page/Page column 15 ; |
|
~%
缬沙坦苄酯 137863-20-8 |
| 文献:Organic Process Research and Development, , vol. 15, # 5 p. 986 - 988 |
| Valsartan benzyl ester |
| L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, phenylmethyl ester |
| Benzyl N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valinate |
| benzyl (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate |
| T5MNNNJ ER BR D1NV4&YVO1R&Y1&1 &&L or S Form |
| Phenylmethyl N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valinate |
| Benzyl N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-L-valinate |
| Benzyl N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valinate |
| Valsartan Impurity 2 |