巴洛沙星结构式
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常用名 | 巴洛沙星 | 英文名 | Balofloxacin |
|---|---|---|---|---|
| CAS号 | 127294-70-6 | 分子量 | 389.42 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 608.3±55.0 °C at 760 mmHg | |
| 分子式 | C20H24FN3O4 | 熔点 | 137ºC | |
| MSDS | 美版 | 闪点 | 321.7±31.5 °C |
巴洛沙星用途Balofloxacin是喹诺酮类抗生素,能通过干扰DNA旋转酶以抑制细菌DNA合成。 |
| 中文名 | 巴罗沙星 |
|---|---|
| 英文名 | Balofloxacin |
| 中文别名 | 巴洛沙星 | 巴洛沙星 | 1-环丙基-7-(3-甲氨基-1-哌啶基)-8-甲氧基-6-氟-1,4-二氢-4-氧代-3-喹啉羧酸 |
| 英文别名 | 更多 |
| 密度 | 1.4±0.1 g/cm3 |
|---|---|
| 沸点 | 608.3±55.0 °C at 760 mmHg |
| 熔点 | 137ºC |
| 分子式 | C20H24FN3O4 |
| 分子量 | 389.42 |
| 闪点 | 321.7±31.5 °C |
| PSA | 60.69000 |
| LogP | 1.24 |
| 外观性状 | 结晶固体 |
| 蒸汽压 | 0.0±1.8 mmHg at 25°C |
| 折射率 | 1.639 |
| 储存条件 | 2-8°C |
| 危险品运输编码 | NONH for all modes of transport |
|---|---|
| 海关编码 | 2933990090 |
| 海关编码 | 2933990090 |
|---|---|
| 中文概述 | 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期 |
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Determination of the new fluoroquinolone balofloxacin and its metabolites in biological fluids by high performance liquid chromatography.
Arzneimittelforschung 45(6) , 716-8, (1995) A sensitive high performance liquid chromatographic method for the determination in biological fluids of 1-cyclopropyl-6-fluoro-1,4- dihydro-8-methoxy-7-(3-methylaminopiperidin-1-yl)-4-oxoquinoline-3 ... |
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Photoallergenicity of a fluoroquinolone antibacterial agent with a fluorine substituent at the 8-position in guinea pigs exposed to long-wavelength UV light.
Skin Pharmacol. Appl. Skin Physiol. 11(4-5) , 232-40, (1998) The 8-position of the quinolone ring of balofloxacin (BLFX), one of fluoroquinolones, was replaced with fluorine to obtain the 8-F. When an aqueous solution of bovine serum albumin (BSA) containing th... |
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Gatifloxacin, moxifloxacin, and balofloxacin resistance due to mutations in the gyrA and parC genes of Staphylococcus epidermidis strains isolated from patients with endophthalmitis, corneal ulcers and conjunctivitis.
Ophthalmic Res. 42(1) , 43-8, (2009) Staphylococcus epidermidis is considered a commensal bacterium; however, it is frequently isolated from ocular infections showing a multidrug resistance. Ciprofloxacin-resistant strains have been isol... |
| (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[3-(methylamino)-1-piperidinyl]-4-oxo-3-quinolinecarboxylic acid |
| q35 |
| MFCD00864925 |
| 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[3-(methylamino)-1-piperidinyl]-4-oxo- |
| baloxin |
| 1-Cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)-1-piperidinyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid |
| BALOFLOXACIN EXTRA PURE |
| 1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
| Balofloxacin |
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