组织蛋白酶D 来源于牛脾脏

更新时间:2024-01-08 19:29:59

组织蛋白酶D 来源于牛脾脏结构式
组织蛋白酶D 来源于牛脾脏结构式
品牌特惠专场
常用名 组织蛋白酶D 来源于牛脾脏 英文名 Cathepsin D, from bovine spleen
CAS号 9025-26-7 分子量 276.351
密度 1.3±0.1 g/cm3 沸点 432.4±45.0 °C at 760 mmHg
分子式 C15H16O3S 熔点 N/A
MSDS 中文版 美版 闪点 215.3±28.7 °C

 组织蛋白酶D 来源于牛脾脏用途


组织蛋白酶D(CTSD)是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

 组织蛋白酶D 来源于牛脾脏名称

中文名 生化酶
英文名 cathepsin d
英文别名 更多

 组织蛋白酶D 来源于牛脾脏生物活性

描述 组织蛋白酶D(CTSD)是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。
相关类别

 组织蛋白酶D 来源于牛脾脏物理化学性质

密度 1.3±0.1 g/cm3
沸点 432.4±45.0 °C at 760 mmHg
分子式 C15H16O3S
分子量 276.351
闪点 215.3±28.7 °C
精确质量 276.082001
LogP 3.16
外观性状 冻干粉
蒸汽压 0.0±1.1 mmHg at 25°C
折射率 1.609
储存条件

-20°C密闭,避光,通风干燥处

稳定性

Unit Definition One unit will produce an increase in A280 of 1.0 per min per mL at pH 3.0 at 37 °C measured as TCA-soluble products using hemoglobin as substrate (1 cm light path).

Physical form Lyophilized powder containing citrate buffer salts

Biochem/physiol Actions Cathepsin D is an endosomal-lysosomal aspartic protease implicated in breast cancer metastasis and Alzheimer’s disease. Lysosomal release of cathepsin D has been found to precede cytochrome c release and loss of membrane potential in apoptotic human foreskin fibroblasts. Cathepsin D levels in PC12 cells increase 12 to 24 hours after apoptosis is induced.

计算化学

1.疏水参数计算参考值(XlogP):2.7

2.氢键供体数量:1

3.氢键受体数量:4

4.可旋转化学键数量:3

5.互变异构体数量:3

6.拓扑分子极性表面积79.7

7.重原子数量:19

8.表面电荷:0

9.复杂度:427

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:2

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

更多

1. 性状: 白色冻干粉末。

2. 密度(g/mL,25℃):未确定

3. 相对蒸汽密度(g/mL,空气=1):未确定

4. 熔点(ºC):未确定

5. 沸点(ºC,常压):未确定

6. 沸点(ºC,5.2kPa):未确定

7. 折射率:未确定

8. 闪点(ºC):未确定

9. 比旋光度(º):未确定

10. 自燃点或引燃温度(ºC):未确定

11. 蒸气压(kPa,20ºC):未确定

12. 饱和蒸气压(kPa,60ºC):未确定

13. 燃烧热(KJ/mol):未确定

14. 临界温度(ºC):未确定

15. 临界压力(KPa):未确定

16. 油水(辛醇/水)分配系数的对数值:未确定

17. 爆炸上限(%,V/V):未确定

18. 爆炸下限(%,V/V):未确定

19. 溶解性:溶于水

 组织蛋白酶D 来源于牛脾脏安全信息

危险品运输编码 NONH for all modes of transport

 组织蛋白酶D 来源于牛脾脏文献50

更多文献
4-tert-Octylphenol stimulates the expression of cathepsins in human breast cancer cells and xenografted breast tumors of a mouse model via an estrogen receptor-mediated signaling pathway.

Toxicology 304 , 13-20, (2013)

Endocrine disrupting chemicals (EDCs) are defined as environmental compounds that modulate steroid hormone receptor-dependent responses an abnormal manner, resulting in adverse health problems for hum...

A periodate-cleavable linker for functional proteomics under slightly acidic conditions: application for the analysis of intracellular aspartic proteases.

J. Proteome Res. 12(1) , 199-207, (2013)

Specific elution of captured proteins greatly improves the quality of proteomic data obtained from pull-downs by avoiding signals from nonspecific proteins, thus allowing more sensitive identification...

Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D release.

Cell Death Dis. 4 , e507, (2013)

Colorectal carcinoma (CRC) is one of the most common causes of cancer-related mortality. Short-chain fatty acids secreted by dietary propionibacteria from the intestine, such as acetate, induce apopto...

 组织蛋白酶D 来源于牛脾脏英文别名

2-[(3-Hydroxy-2-butanyl)sulfanyl]-3-methyl-1,4-naphthoquinone
1,4-Naphthalenedione, 2-[(2-hydroxy-1-methylpropyl)thio]-3-methyl-
2-[(3-hydroxybutan-2-yl)sulfanyl]-3-methylnaphthalene-1,4-dione
MFCD00130749