雌三醇-16beta-D-葡糖苷酸

更新时间:2024-01-04 18:08:11

雌三醇-16beta-D-葡糖苷酸结构式
雌三醇-16beta-D-葡糖苷酸结构式
品牌特惠专场
常用名 雌三醇-16beta-D-葡糖苷酸 英文名 Estriol 16α-(β-D-glucuronide)
CAS号 1852-50-2 分子量 464.50500
密度 1.51g/cm3 沸点 738.3ºC at 760mmHg
分子式 C24H32O9 熔点 N/A
MSDS 中文版 美版 闪点 253.5ºC
符号 GHS08
GHS08
信号词 Warning

 雌三醇-16beta-D-葡糖苷酸用途


雌二醇16α-(β-D-葡萄糖醛酸)是尿中的内源性代谢产物,可用于妊娠研究[1][2]。

 雌三醇-16beta-D-葡糖苷酸名称

中文名 雌三醇-16beta-D-葡糖苷酸
英文名 Estriol-16beta-D-glucopyranosiduronic acid
中文别名 3,17B-二羟基-1,3,5(10)-雌甾三烯-16A-基-BETA-D-葡糖苷酸 | 雌三醇-16alfa-(beta-D-葡糖苷酸)
英文别名 更多

 雌三醇-16beta-D-葡糖苷酸生物活性

描述 雌二醇16α-(β-D-葡萄糖醛酸)是尿中的内源性代谢产物,可用于妊娠研究[1][2]。
相关类别
体外研究 内源性代谢产物被定义为《京都基因和基因组百科全书》注释为我们基因组中约1900种代谢酶的底物或产物。在文献正文中很清楚,许多这些代谢产物都具有毒性[1]。
参考文献

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.  

[2]. Yang YJ, et al. Direct determination of estriol 3- and 16-glucuronides in pregnancy urine by column-switching liquid chromatography with electrospray tandem mass spectrometry. Biomed Chromatogr. 2003 Jun;17(4):219-25.  

 雌三醇-16beta-D-葡糖苷酸物理化学性质

密度 1.51g/cm3
沸点 738.3ºC at 760mmHg
分子式 C24H32O9
分子量 464.50500
闪点 253.5ºC
精确质量 464.20500
PSA 156.91000
LogP 0.49650
蒸汽压 6.95E-23mmHg at 25°C
折射率 1.667
储存条件 -20°C

 雌三醇-16beta-D-葡糖苷酸安全信息

符号 GHS08
GHS08
信号词 Warning
危害声明 H351
警示性声明 P281
个人防护装备 dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲) Xn: Harmful;
风险声明 (欧洲) 40
安全声明 (欧洲) 36/37
危险品运输编码 NONH for all modes of transport
WGK德国 3

 雌三醇-16beta-D-葡糖苷酸文献31

更多文献
Radioimmunoassay of 2-hydroxyestrone.

Steroids 31(2) , 249-58, (1978)

Under the protection of ascorbic acid a 2-hydroxyestrone bovine serum albumin conjugate was prepared containing intact 2-hydroxyestrone as determined by gas chromatographymass spectometry. Using this ...

The dynamic changes of several reproductive hormones during termination of early pregnancy by RU486 in combination with PG-05 in Chinese women.

Adv. Contracept. 4(4) , 319-26, (1988)

8 pregnant women (below 49 days of amenorrhea) were administered 600 mg RU486 orally in a single dosage, and 1 mg PG-05 as a vaginal suppository 48 h afterwards. The plasma beta-hCG, progesterone, 17 ...

Associations between urinary phthalate monoesters and thyroid hormones in pregnant women.

Hum. Reprod. 22(10) , 2715-22, (2007)

Maternal hypothyroidism during pregnancy can cause adverse effects in the fetus. Scientific evidence has shown that probable thyroid-like function of some phthalates in vitro and in vivo, and phthalat...

 雌三醇-16beta-D-葡糖苷酸英文别名

estriol 16 glucuronide
Estriol O16-glucuronide