| 常用名 | PBT434 | CAS号 | 1232841-78-9 |
|---|---|---|---|
| 价格 | $650.0/100mg $1100.0/250mg $2200.0/1g | 纯度 | 98.0% |
| 备货期 | 3天 | 库存 | 现货 |
| 产品网页 | https://www.dcchemicals.com/product_show-DC22191.html | ||
| 产品详情(用途,包装等)
PBT434 is a novel quinazolinone compound with effect of lowering cellular iron levels, prevents iron mediated neurodegeneration and α-synuclein toxicity in multiple models of Parkinson disease; inhibits iron-mediated redox activity and iron-mediated aggregation of α-synuclein, a protein that aggregates in the neuropathology; prevents loss of substantia nigra pars compacta neurons (SNpc), lowers nigral α-synuclein accumulation, and rescues motor performance in mice model of PD. |