Il Farmaco

1, 2, 3-triazolo [4, 5-h] quinolines: III: preparation and antimicrobial evaluation of 4-ethyl-4, 7-dihydro-1 (2)-R-1 (2) H triazolo [4, 5-h] quinolin-7-one-6-carboxylic acids …

PA Sanna, A Carta, G Paglietti, SAL Zanetti, G Fadda

文献索引：Sanna; Carta; Paglietti; Zanetti; Fadda Farmaco, 1992 , vol. 47, # 7-8 p. 1001 - 1019

全文：HTML全文

被引用次数: 18

摘要

Some 4-ethyl-1 (2)-R-1 (2) H-4, 7-dihydro-triazolo [4, 5-h]-quinolin-7-one-6-carboxylic acids were prepared as novel analogues of oxolinic acid, in order to discover the influence of the annelation position of the triazole ring on the antimicrobial activity that, in some isomers triazolo [4, 5-f] quinoline carboxylic acids, is selective against Escherichia coli. Some interesting side reactions in the cyclization of 1 (2)-R-1 (2) H-benzotriazol-4-yl- ...