L-Pyroglutamicacid

Modify Date: 2024-01-02 15:14:01

L-Pyroglutamicacid Structure
L-Pyroglutamicacid structure
Common Name L-Pyroglutamicacid
CAS Number 98-79-3 Molecular Weight 129.114
Density 1.6±0.1 g/cm3 Boiling Point 382.4±52.0 °C at 760 mmHg
Molecular Formula C5H7NO3 Melting Point 160-163 °C(lit.)
MSDS Chinese USA Flash Point 185.1±30.7 °C

 Use of L-Pyroglutamicacid


L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

 Names

Name 5-oxo-L-proline
Synonym More Synonyms

 L-Pyroglutamicacid Biological Activity

Description L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.
Related Catalog
Target

Human Endogenous Metabolite

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 382.4±52.0 °C at 760 mmHg
Melting Point 160-163 °C(lit.)
Molecular Formula C5H7NO3
Molecular Weight 129.114
Flash Point 185.1±30.7 °C
Exact Mass 129.042587
PSA 66.40000
LogP -1.95
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.627
Water Solubility 10-15 g/100 mL (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TW3710000
CHEMICAL NAME :
Proline, 5-oxo-, L-
CAS REGISTRY NUMBER :
98-79-3
LAST UPDATED :
199807
DATA ITEMS CITED :
2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4882359
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4882359

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS TW3710000
HS Code 2933790090

 Synthetic Route

 Customs

HS Code 2933790090
Summary 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

 Articles68

More Articles
Physiology and pathophysiology of organic acids in cerebrospinal fluid.

J. Inherit. Metab. Dis. 16(4) , 648-69, (1993)

Concentrations of organic acids in cerebrospinal fluid (CSF) appear to be directly dependent upon their rate of production in the brain. There is evidence that the net release of short-chain monocarbo...

Age-related reference values for urinary organic acids in a healthy Turkish pediatric population.

Clin. Chem. 40(6) , 862-6, (1994)

Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days...

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.

Nature 457(7231) , 910-4, (2009)

Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the i...

 Synonyms

EINECS 202-700-3
MFCD00005272
L-Pyroglutamicacid
hydroxy-pyridin-3-yl-acetic acid
5 oxoproline
L-Pyroglutamic acid
H-Pyr-OH
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Price: ¥550/10 mM * 1 mL in DMSO

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