(S)-Venlafaxine

Modify Date: 2024-01-01 20:40:29

(S)-Venlafaxine Structure
(S)-Venlafaxine structure
Common Name (S)-Venlafaxine
CAS Number 93413-44-6 Molecular Weight 277.40200
Density 1.06g/cm3 Boiling Point 397.575ºC at 760 mmHg
Molecular Formula C17H27NO2 Melting Point 102-104ºC
MSDS N/A Flash Point 194.246ºC

 Use of (S)-Venlafaxine


(S)-Venlafaxine is the (S)-configuration of Venlafaxine. Venlafaxine is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant agent[1].

 Names

Name 1-[(1S)-2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol
Synonym More Synonyms

 (S)-Venlafaxine Biological Activity

Description (S)-Venlafaxine is the (S)-configuration of Venlafaxine. Venlafaxine is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant agent[1].
Related Catalog
References

[1]. Bymaster FP, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.

 Chemical & Physical Properties

Density 1.06g/cm3
Boiling Point 397.575ºC at 760 mmHg
Melting Point 102-104ºC
Molecular Formula C17H27NO2
Molecular Weight 277.40200
Flash Point 194.246ºC
Exact Mass 277.20400
PSA 32.70000
LogP 3.03560
Index of Refraction 1.544

 Synthetic Route

 Synonyms

1-[(1S)-2-(DIMETHYLAMINO)-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANOL
(S)-VENLAFAXINE
R(-)-1-[2-(dimethylamino)-1-(4-methoxyphenyl)-ethyl]cyclohexanol
(-)-Venlafaxine
(1R)-1-[2-dimethylamino-1-(4-methoxy-phenyl)-ethyl]cyclohexanol
BIDD:GT0838
R-venlafaxine