Triazavirin
Modify Date: 2024-01-02 11:47:48
Triazavirin structure
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Common Name | Triazavirin | ||
|---|---|---|---|---|
| CAS Number | 928659-17-0 | Molecular Weight | 286.201 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C5H7N6NaO5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TriazavirinTriazavirin (Riamilovir sodium dihydrate) is a broad-spectrum antiviral agent targeting influenza viruses, lassa virus, TBEV and Ebola virus; suppresses the replication of influenza virus in cell culture and in chicken chorioallantoic membranes, and protects mice from death caused by type A and B influenza viruses. |
| Name | Riamilovir Sodium Dihydrate |
|---|---|
| Synonym | More Synonyms |
| Description | Triazavirin (Riamilovir sodium dihydrate) is a broad-spectrum antiviral agent targeting influenza viruses, lassa virus, TBEV and Ebola virus; suppresses the replication of influenza virus in cell culture and in chicken chorioallantoic membranes, and protects mice from death caused by type A and B influenza viruses. |
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| Related Catalog | |
| Target |
Nucleoside analogue; Influenza virus[1] |
| In Vitro | The efficacy of Triazavirin against the tick-borne encephalitis virus is estimated in the sensitive cell culture. In a concentration of 128 mcg/mL Triazavirin is shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin) by accumulation in the SKEV cell culture[2]. |
| In Vivo | The therapeutic efficacy Triazavirin against experimental Forest-Spring encephalitis on albino mice is studied. The results shows that in high doses (200-400 mg/kg) Triazavirin moderately protects the infected animals. A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically valid decrease of the virus accumulation in the target organ are observed[3]. |
| References |
| Molecular Formula | C5H7N6NaO5S |
|---|---|
| Molecular Weight | 286.201 |
| Exact Mass | 286.009644 |
| Riamilovir Sodium Dihydrate |
| Sodium 7-(methylsulfanyl)-3-nitro-4-oxo-4H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-1-ide hydrate (1:1:2) |
| [1,2,4]Triazolo[5,1-c][1,2,4]triazin-4(1H)-one, 7-(methylthio)-3-nitro-, sodium salt, hydrate (1:1:2) |