SIRT6-IN-5

Modify Date: 2024-02-04 08:55:55

SIRT6-IN-5 structure	Common Name	SIRT6-IN-5
	CAS Number	891002-11-2	Molecular Weight	366.32
	Density	1.5±0.1 g/cm3	Boiling Point	461.6±45.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₁₄N₂O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	233.0±28.7 °C

Use of SIRT6-IN-5

SIRT6-IN-2 (Compound 5) is a selective SIRT6 inhibitor (IC50: 34 μM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects[1].

Name	5-{[4-(2-Furoylamino)benzoyl]amino}-2-hydroxybenzoic acid
Synonym	More Synonyms

Description	SIRT6-IN-2 (Compound 5) is a selective SIRT6 inhibitor (IC50: 34 μM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects[1].
Related Catalog	Signaling Pathways >> Epigenetics >> Sirtuin Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin
Target	SIRT6[1]
References	[1]. Damonte P, et al. SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects. Bioorg Med Chem. 2017 Oct 15;25(20):5849-5858.

Density	1.5±0.1 g/cm3
Boiling Point	461.6±45.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₄N₂O₆
Molecular Weight	366.32
Flash Point	233.0±28.7 °C
Exact Mass	366.085175
LogP	3.39
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.733

5-{[4-(2-Furoylamino)benzoyl]amino}-2-hydroxybenzoic acid

MFCD07114223

Benzoic acid, 5-[[4-[(2-furanylcarbonyl)amino]benzoyl]amino]-2-hydroxy-

DC Chemicals Limited
China
Product Name: SIRT6-IN-5
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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Price: ￥1500/5 mg

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SIRT6-IN-5

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