4-Nitrophthalimide

Modify Date: 2024-01-03 18:43:33

4-Nitrophthalimide Structure
4-Nitrophthalimide structure
Common Name 4-Nitrophthalimide
CAS Number 89-40-7 Molecular Weight 192.128
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C8H4N2O4 Melting Point 206 °C
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-Nitrophthalimide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Melting Point 206 °C
Molecular Formula C8H4N2O4
Molecular Weight 192.128
Exact Mass 192.017105
PSA 91.99000
LogP 0.88
Index of Refraction 1.658
Stability Stable. Combustible. Incompatible with moisture, water, strong oxidising agents, strong bases.
Water Solubility <0.01 g/100 mL at 18 ºC

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TI5625000
CHEMICAL NAME :
Phthalimide, 4-nitro-
CAS REGISTRY NUMBER :
89-40-7
BEILSTEIN REFERENCE NO. :
0180224
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H4-N2-O4
MOLECULAR WEIGHT :
192.14

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
333 ug/plate
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S37/39-S26
RIDADR NONH for all modes of transport
RTECS TI5625000
HS Code 2925190090

 Synthetic Route

~87%

4-Nitrophthalimide Structure

4-Nitrophthalimide

CAS#:89-40-7

Literature: Yang, Na; Wang, Qing-He; Wang, Wen-Qian; Wang, Jian; Li, Feng; Tan, Shen-Peng; Cheng, Mao-Sheng Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 53 - 56

~90%

4-Nitrophthalimide Structure

4-Nitrophthalimide

CAS#:89-40-7

Literature: Peng; Song; Qian Synthetic Communications, 2001 , vol. 31, # 12 p. 1927 - 1931

~56%

4-Nitrophthalimide Structure

4-Nitrophthalimide

CAS#:89-40-7

Literature: Jacq, Jerome; Berthiol, Florian; Einhorn, Cathy; Einhorn, Jacques Synlett, 2010 , # 15 p. 2263 - 2266

~%

4-Nitrophthalimide Structure

4-Nitrophthalimide

CAS#:89-40-7

Literature: Synthetic Communications, , vol. 33, # 9 p. 1499 - 1507

~%

4-Nitrophthalimide Structure

4-Nitrophthalimide

CAS#:89-40-7

Literature: US2195076 , ; DE767834 , ; DRP/DRBP Org.Chem.

~%

4-Nitrophthalimide Structure

4-Nitrophthalimide

CAS#:89-40-7

Literature: Carbohydrate Polymers, , vol. 80, # 3 p. 839 - 844

~%

4-Nitrophthalimide Structure

4-Nitrophthalimide

CAS#:89-40-7

Literature: Chemische Berichte, , vol. 33, p. 2811

~%

4-Nitrophthalimide Structure

4-Nitrophthalimide

CAS#:89-40-7

Literature: Canadian Journal of Chemistry, , vol. 63, p. 121 - 128

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles3

More Articles
An approach for evaluating and increasing the informational content of mutagenicity and clastogenicity data bases.

Mutagenesis 8(3) , 257-64, (1993)

A method is described for using the fragments identified by the CASE structure-activity relational expert system to identify the type of chemicals that require further testing in mutagenicity and clas...

Colorimetric detection of achiral anions and chiral carboxylates by a chiral thiourea-phthalimide dyad.

Photochem. Photobiol. Sci. 9(10) , 1385-90, (2010)

The chiral chemosensor 1, based on a thiourea-activated phthalimide, is available by four reaction steps from 4-nitrophthalimide. 1 detects fluoride, chloride, acetate, and dihydrogen phosphate anions...

Design, synthesis and protection against pentylenetetrazole-induced seizure of N-aryl derivatives of the phthalimide pharmacophore.

Med. Chem. 8(5) , 953-63, (2012)

A series of compounds including N-aryl substituents of phthalimide and 4-nitrophthalimide were synthesized and evaluated for their anticonvulsant properties. The in vivo screening data suggest that al...

 Synonyms

1H-Isoindole-1,3(2H)-dione, 5-nitro-
4-Nitrophthalimide
4-nitro-phthalimid
5-NITROPHTHALIMIDE
4-Nitrophtalimide
5-Nitro-1H-isoindole-1,3(2H)-dione
3-nitrophthalimide
4-Nirtophthalimide
5-Nitroisoindoline-1,3-dione
5-Nitro-isoindolin-1,3-dion
4-nitro-phthalimide
5-nitrosoindoline-1,3-dione
EINECS 201-905-5
5-nitro-isoindole-1,3-dione
P-NITRO-PHTHALIMIDE
PHTHALIMIDE,4-NITRO
MFCD00005884
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