(7R)-2-Chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-6(5H)-pteridinone

Modify Date: 2023-01-15 21:57:15

(7R)-2-Chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-6(5H)-pteridinone Structure
(7R)-2-Chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-6(5H)-pteridinone structure
Common Name (7R)-2-Chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-6(5H)-pteridinone
CAS Number 877676-50-1 Molecular Weight 268.743
Density 1.2±0.1 g/cm3 Boiling Point 492.1±40.0 °C at 760 mmHg
Molecular Formula C12H17ClN4O Melting Point N/A
MSDS N/A Flash Point 251.4±27.3 °C

 Names

Name (7R)-2-Chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydro-6(5H)-pter idinone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 492.1±40.0 °C at 760 mmHg
Molecular Formula C12H17ClN4O
Molecular Weight 268.743
Flash Point 251.4±27.3 °C
Exact Mass 268.109100
PSA 49.33000
LogP 0.82
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.541

 Safety Information

HS Code 2933990090

 Synthetic Route

~84%

(7R)-2-Chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-6(5H)-pteridinone Structure

(7R)-2-Chloro-7...

CAS#:877676-50-1

Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH Patent: WO2009/19205 A1, 2009 ; Location in patent: Page/Page column 14 ;

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(7R)-2-Chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-6(5H)-pteridinone Structure

(7R)-2-Chloro-7...

CAS#:877676-50-1

Literature: Bowers, Simeon; Truong, Anh P.; Ye, Michael; Aubele, Danielle L.; Sealy, Jennifer M.; Neitz, R. Jeffrey; Hom, Roy K.; Chan, Wayman; Dappen, Michael S.; Galemmo Jr., Robert A.; Konradi, Andrei W.; Sham, Hing L.; Zhu, Yong L.; Beroza, Paul; Tonn, George; Zhang, Heather; Hoffman, Jennifer; Motter, Ruth; Fauss, Donald; Tanaka, Pearl; Bova, Michael P.; Ren, Zhao; Tam, Danny; Ruslim, Lany; Baker, Jeanne; Pandya, Deepal; Diep, Linnea; Fitzgerald, Kent; Artis, Dean R.; Anderson, John P.; Bergeron, Marcelle Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2743 - 2749

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(7R)-2-Chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-6(5H)-pteridinone Structure

(7R)-2-Chloro-7...

CAS#:877676-50-1

Literature: SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.; JIANGSU HENGRUI MEDICINE CO., LTD. Patent: US2012/184543 A1, 2012 ; Title/Abstract Full Text Show Details Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co. Ltd. Patent: EP2481739 A1, 2012 ;

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(R)-2-chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydropteridin-6(5H)-one
(7R)-2-Chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-6(5H)-pteridinone
(7R)-2-Chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydro-6(5H)-pteridinone
2-chloro-7,8-dimethyl-3-quinolinecarbaldehyde
2-chloro-7,8-dimethyl-3-quinolinecarboxaldehyde
2-chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-(7R)-6(5H)-pteridinone
(7R)-2-chloro-7-ethyl-8-isopropyl-5-methyl-7H-pteridin-6-one
2-Chloro-7,8-dimethylquinoline-3-carboxaldehyde
(R)-2-chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydro-5H-pteridin-6-one
6(5H)-Pteridinone, 2-chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-, (7R)-
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