retronecine hydrochloride

Modify Date: 2024-01-18 16:31:41

retronecine hydrochloride Structure
retronecine hydrochloride structure
Common Name retronecine hydrochloride
CAS Number 875-22-9 Molecular Weight 191.65500
Density 1.29g/cm3 Boiling Point 291.3ºC at 760 mmHg
Molecular Formula C8H14ClNO2 Melting Point N/A
MSDS N/A Flash Point 161.4ºC

 Names

Name retronecine hydrochloride

 Chemical & Physical Properties

Density 1.29g/cm3
Boiling Point 291.3ºC at 760 mmHg
Molecular Formula C8H14ClNO2
Molecular Weight 191.65500
Flash Point 161.4ºC
Exact Mass 191.07100
PSA 43.70000
LogP 0.09380

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VH7350000
CHEMICAL NAME :
Retronecine hydrochloride
CAS REGISTRY NUMBER :
875-22-9
LAST UPDATED :
199012
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H13-N-O2.Cl-H
MOLECULAR WEIGHT :
191.68
WISWESSER LINE NOTATION :
T55 AN CUTJ D1Q FQ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - acute pulmonary edema Liver - other changes
REFERENCE :
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 185,842,1960
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 49,665,1972 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Spinal Cord - tumors
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 49,665,1972 *** REVIEWS *** TOXICOLOGY REVIEW CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 60,1171,1976
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