Fmoc-NH-PEG3-CH2CH2COOH

Modify Date: 2024-01-02 12:20:55

Fmoc-NH-PEG3-CH2CH2COOH Structure
Fmoc-NH-PEG3-CH2CH2COOH structure
Common Name Fmoc-NH-PEG3-CH2CH2COOH
CAS Number 867062-95-1 Molecular Weight 443.490
Density 1.2±0.1 g/cm3 Boiling Point 651.9±55.0 °C at 760 mmHg
Molecular Formula C24H29NO7 Melting Point N/A
MSDS N/A Flash Point 348.0±31.5 °C

 Use of Fmoc-NH-PEG3-CH2CH2COOH


Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid
Synonym More Synonyms

 Fmoc-NH-PEG3-CH2CH2COOH Biological Activity

Description Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Kyoji TSUCHIKAMA, et al. Linkers for antibody drug conjugates. WO2018218004A1.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 651.9±55.0 °C at 760 mmHg
Molecular Formula C24H29NO7
Molecular Weight 443.490
Flash Point 348.0±31.5 °C
Exact Mass 443.194397
PSA 103.32000
LogP 2.66
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.562
Storage condition 2-8°C

 Safety Information

HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2,7,10,13-Tetraoxa-4-azahexadecan-16-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
2-[2-[2-(2-aminoethoxy)ethoxy]ethoxymethyl]-3-(9H-fluoren-9-ylmethoxy)-3-oxopropanoic acid
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid
Fmoc-12-Amino-4,7,10-Trioxadodecanoic Acid
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