pre-Calcitriol PTAD Adduct

Modify Date: 2024-01-02 18:17:11

pre-Calcitriol PTAD Adduct Structure
pre-Calcitriol PTAD Adduct structure
 Common Name pre-Calcitriol PTAD Adduct
CAS Number 86307-44-0 Molecular Weight 591.78100
Density N/A Boiling Point N/A
Molecular Formula C35H49N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of pre-Calcitriol PTAD Adduct


Impurity C of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).IC50 value:Target: vitamin D receptorCalcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) displays calcemic actions. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol )exhibits antitumor activity; Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells.

 Names

Name pre-Calcitriol PTAD Adduct
Synonym More Synonyms

 pre-Calcitriol PTAD Adduct Biological Activity

Description Impurity C of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).IC50 value:Target: vitamin D receptorCalcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) displays calcemic actions. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol )exhibits antitumor activity; Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells.
Related Catalog
References

[1]. Canalejo et al (2000) The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosis. J.Am.Soc.Nephrol. 11 1865. Beer and Myrthue (2004)

[2]. Calcitriol in cancer treatment: from the lab to the clinic. Mol.Cancer Ther. 3 373.

[3]. Krishnan AV, Swami S, Feldman D.Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: Importance of mammary CYP27B1 for treatment and prevention.J Steroid Biochem Mol Biol. 2012 Aug 23.

[4]. Alkharfy KM, Al-Daghri NM, Yakout SM, Ahmed M. Calcitriol Attenuates Weight-Related Systemic Inflammation and Ultrastructural Changes of the Liver in a Rodent Model.Basic Clin Pharmacol Toxicol. 2012 Aug 21.

 Chemical & Physical Properties

Molecular Formula C35H49N3O5
Molecular Weight 591.78100
Exact Mass 591.36700
PSA 109.62000
LogP 5.05860
Storage condition 2-8℃

 Synonyms

Impurity C of Calcitriol
Calcitriol Impurity 3
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Chemsrc provides pre-Calcitriol PTAD Adduct(CAS#:86307-44-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of pre-Calcitriol PTAD Adduct are included as well.>> amp version: pre-Calcitriol PTAD Adduct

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