o-Xylylene N,N-Diethylphosphoramidite

Modify Date: 2024-01-14 12:35:53

o-Xylylene N,N-Diethylphosphoramidite Structure
o-Xylylene N,N-Diethylphosphoramidite structure
Common Name o-Xylylene N,N-Diethylphosphoramidite
CAS Number 82372-35-8 Molecular Weight 239.251
Density 1.11 g/mL at 20ºC(lit.) Boiling Point 255.3±30.0 °C at 760 mmHg
Molecular Formula C12H18NO2P Melting Point N/A
MSDS USA Flash Point 108.2±24.6 °C

 Names

Name N,N-Diethyl-1,5-dihydro-2,4,3-benzodioxaphosphepin-3-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.11 g/mL at 20ºC(lit.)
Boiling Point 255.3±30.0 °C at 760 mmHg
Molecular Formula C12H18NO2P
Molecular Weight 239.251
Flash Point 108.2±24.6 °C
Exact Mass 239.107513
PSA 35.29000
LogP 2.42
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction n20/D 1.541(lit.)
Storage condition 2-8℃

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
RIDADR NA 1993 / PGIII

 Synthetic Route

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o-Xylylene N,N-Diethylphosphoramidite Structure

o-Xylylene N,N-...

CAS#:82372-35-8

Literature: Journal of Organometalic Chemistry, , vol. 646, # 1-2 p. 239 - 246

~61%

o-Xylylene N,N-Diethylphosphoramidite Structure

o-Xylylene N,N-...

CAS#:82372-35-8

Literature: Arbuzov, B. A.; Kadyrov, R. A.; Klochkov, V. V.; Arshinova, R. P.; Aganov, A. V. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1982 , vol. 31, # 3 p. 520 - 525 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1982 , # 3 p. 588 - 593

 Articles3

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A scalable synthesis of the IP7 isomer, 5-PP-Ins(1,2,3,4,6)P5.

Org. Lett. 11(7) , 1551-1554, (2009)

The phosphorylated inositol diphosphates, including the diphosphoinositol pentakisphosphate regioisomers, play critical roles in signal transduction and cellular regulation. In particular, the IP(7) i...

Synergistic inhibition of human Synergistic inhibition of human α-1, 3-fucosyltransferase V. Qiao L, et al

J. Am. Chem. Soc. 118(33) , 7653-7662, (1996)

Utilization of O-xylylene N,N-diethylphosphoramidite for the synthesis of phosphoric diesters. Watanabe Y, et al

Tetrahedron Lett. 33(10) , 1313-1316, (1992)

 Synonyms

N,N-Diethyl-1,5-dihydro-2,4,3-benzodioxaphosphepin-3-amine
N,N-diethyl-1,5-dihydrobenzo[e][1,3,2]dioxaphosphepin-3-amine
(1,5-dihydro-benzo[e][1,3,2]dioxaphosphepin-3-yl)-diethylamine
1,5-dihydro-3-diethylamino-2,4,3-benzodioxaphosphepine
o-xylylene-N,N-diethylphosphoramidite
3-(Diethylamino)-1,5-dihydro-2,4,3-benzodioxaphosphepine
N,N-diethyl-1,5-dihydro-3H-2,3,4-benzodioxaphosphepin-3-amine
MFCD00192025
(1,5-Dihydro-benzo[e][1,3,2]dioxaphosphepin-3-yl)-diethyl-amine
2,4,3-Benzodioxaphosphepin-3-amine, N,N-diethyl-1,5-dihydro-
3-(Diethylamino)-1,5-dihydro-2,4,3-benzodioxaphosphepin
N,N-diethyl-1,5-dihydro-3H-2,4,3-benzodioxaphosphepin-3-amine
o-Xylylene N,N-Diethylphosphoramidite