4,4'-Dichlorodiphenyl sulfone

Modify Date: 2024-01-02 16:46:06

4,4'-Dichlorodiphenyl sulfone Structure
4,4'-Dichlorodiphenyl sulfone structure
Common Name 4,4'-Dichlorodiphenyl sulfone
CAS Number 80-07-9 Molecular Weight 287.162
Density 1.4±0.1 g/cm3 Boiling Point 419.9±0.0 °C at 760 mmHg
Molecular Formula C12H8Cl2O2S Melting Point 143-146 °C(lit.)
MSDS Chinese USA Flash Point 211.2±24.6 °C

 Names

Name 4,4‘-Dichlorodiphenyl sulfone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 419.9±0.0 °C at 760 mmHg
Melting Point 143-146 °C(lit.)
Molecular Formula C12H8Cl2O2S
Molecular Weight 287.162
Flash Point 211.2±24.6 °C
Exact Mass 285.962219
PSA 42.52000
LogP 4.20
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.610
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility <0.1 g/100 mL at 20 ºC

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WR3450000
CHEMICAL NAME :
Sulfone, bis(p-chlorophenyl)
CAS REGISTRY NUMBER :
80-07-9
BEILSTEIN REFERENCE NO. :
2052955
LAST UPDATED :
199712
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C12-H8-Cl2-O2-S
MOLECULAR WEIGHT :
287.16
WISWESSER LINE NOTATION :
GR DSWR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7500 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533718
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
24 gm/kg
TOXIC EFFECTS :
Behavioral - tremor
REFERENCE :
HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 29,1317,1946 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
364 mg/kg/26W-I
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Liver - liver function tests impaired
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 47(2),84,1982 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 10 ppm JAN 1993

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S22-S24/25-S37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS WR3450000
HS Code 29309070

 Synthetic Route

 Customs

HS Code 2904909090
Summary HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Articles15

More Articles
Enantiomeric specificity of methylsulfonyl-PCBs and distribution of bis(4-chlorophenyl) sulfone, PCB, and DDE methyl sulfones in grey seal tissues.

Environ. Sci. Technol. 38(19) , 4950-5, (2004)

PCB methyl sulfones (MeSO2-PCBs) are lipophilic PCB metabolites of which five of the environmentally relevant meta/para pairs are chiral (i.e., exist as atropisomeric pairs). Methylsulfonyl-DDE (MeSO2...

Temporal trend of bis(4-chlorophenyl) sulfone, methylsulfonyl-DDE and -PCBs in Baltic guillemot (Uria aalge) egg 1971-2001--a comparison to 4,4'-DDE and PCB trends.

Environ. Pollut. 141(2) , 226-37, (2006)

The dynamics of organohalogen contaminants and their metabolites are best studied over time by analysis of biota at high trophic levels. In this study, time trends, 1971-2001, of bis(4-chlorophenyl) s...

Immobilization of Mucor miehei Lipase onto Macroporous Aminated Polyethersulfone Membrane for Enzymatic Reactions.

Membranes (Basel.) 2 , 198-213, (2014)

Immobilization of enzymes is one of the most promising methods in enzyme performance enhancement, including stability, recovery, and reusability. However, investigation of suitable solid support in en...

 Synonyms

EINECS 201-247-9
1,1'-Sulfonylbis(4-chlorobenzene)
Benzene, 1,1'-sulfonylbis[4-chloro-
4,4'-Dichlorodiphenylsulfone
Bis(4-chlorophenyl) sulfone
1-chloro-4-(4-chlorophenyl)sulfonylbenzene
MFCD00000619
4,4'-Dichlorodiphenyl sulfone