Roxatidine

Modify Date: 2024-01-03 09:50:53

Roxatidine Structure
Roxatidine structure
Common Name Roxatidine
CAS Number 78273-80-0 Molecular Weight 306.40000
Density 1.137 g/cm3 Boiling Point 524.3ºC at 760 mmHg
Molecular Formula C17H26N2O3 Melting Point N/A
MSDS N/A Flash Point 270.9ºC

 Use of Roxatidine


Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is a histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect[1].

 Names

Name Roxatidine
Synonym More Synonyms

 Roxatidine Biological Activity

Description Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is a histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect[1].
Related Catalog
References

[1]. Lee M, et al. Roxatidine attenuates mast cell-mediated allergic inflammation via inhibition of NF-κB and p38 MAPK activation. Sci Rep. 2017;7:41721. Published 2017 Jan 31.

 Chemical & Physical Properties

Density 1.137 g/cm3
Boiling Point 524.3ºC at 760 mmHg
Molecular Formula C17H26N2O3
Molecular Weight 306.40000
Flash Point 270.9ºC
Exact Mass 306.19400
PSA 61.80000
LogP 1.87870

 Safety Information

HS Code 2933399090

 Synthetic Route

~96%

Roxatidine Structure

Roxatidine

CAS#:78273-80-0

Literature: Snow Brand Milk Products Co., Ltd. Patent: US5317026 A1, 1994 ;

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Roxatidine Structure

Roxatidine

CAS#:78273-80-0

Literature: US4293557 A1, ;

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

ROXATIDINE ENTERPRISE STANDARD
MFCD00871807
desacetyl-TZU-0460
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  • DC Chemicals Limited
  • China
  • Product Name: Roxatidine
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
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Price: ¥2400/5 mg

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