4-Hydroxy-3-methoxystyrene

Modify Date: 2024-01-02 23:30:57

4-Hydroxy-3-methoxystyrene structure	Common Name	4-Hydroxy-3-methoxystyrene
	CAS Number	7786-61-0	Molecular Weight	150.174
	Density	1.1±0.1 g/cm3	Boiling Point	245.0±20.0 °C at 760 mmHg
	Molecular Formula	C₉H₁₀O₂	Melting Point	25-29°C
	MSDS	Chinese USA	Flash Point	111.3±6.7 °C
	Symbol	GHS07	Signal Word	Warning

Use of 4-Hydroxy-3-methoxystyrene

2-Methoxy-4-vinylphenol (2M4VP), a naturally Germination inhibitor, exerts potent anti-inflammatory effects[1][2].

Name	2-methoxy-4-vinylphenol
Synonym	More Synonyms

Description	2-Methoxy-4-vinylphenol (2M4VP), a naturally Germination inhibitor, exerts potent anti-inflammatory effects[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	2-Methoxy-4-vinylphenol (2M4VP) potently inhibits the translocation of NF-κB p65 into the nucleus by IκB degradation following IκB-α phosphorylation and the phosphorylation of MAPKs such as p38, ERK1/2, and JNK[1]. 2-Methoxy-4-vinylphenol (2M4VP) inhibits hyper-acetylation of histone H3 (Lys9/Lys14) induced by LPS[1]. Western Blot Analysis[1] Cell Line: RAW264.7 cells. Concentration: 0-40 μM. Incubation Time: 24 h. Result: Inhibited the over-expression of iNOS and COX-2 protein in LPS-stimulated RAW264.7 cells.
References	[1]. Jin Boo Jeong, et al. Anti-inflammatory Effect of 2-methoxy-4-vinylphenol via the Suppression of NF-κB and MAPK Activation, and Acetylation of Histone H3. Arch Pharm Res. 2011 Dec;34(12):2109-16. [2]. Hossein Reza Darabi, et al. A Structure-Activity Relationship Study on a Natural Germination Inhibitor, 2-methoxy-4-vinylphenol (MVP), in Wheat Seeds to Evaluate Its Mode of Action. Z Naturforsch C J Biosci. Sep-Oct 2007;62(9-10):694-700.

Density	1.1±0.1 g/cm3
Boiling Point	245.0±20.0 °C at 760 mmHg
Melting Point	25-29°C
Molecular Formula	C₉H₁₀O₂
Molecular Weight	150.174
Flash Point	111.3±6.7 °C
Exact Mass	150.068085
PSA	29.46000
LogP	1.93
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.578
Storage condition	2-8°C

4-Hydroxy-3-methoxystyrene MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL8205000

CHEMICAL NAME :: Phenol, 2-methoxy-4-vinyl-

CAS REGISTRY NUMBER :: 7786-61-0

BEILSTEIN REFERENCE NO. :: 2044521

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H10-O2

MOLECULAR WEIGHT :: 150.19

WISWESSER LINE NOTATION :: 1U1R DQ CO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1400 mg/kg

SEX/DURATION :: female 7 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Fertility - other measures of fertility

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 500 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,17,1988

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	SL8205000
HS Code	2909500000

Precursor 9
CAS#:141-82-2 Malonic acid CAS#:121-33-5 Vanillin CAS#:1779-49-3 Methyltriphenyl... CAS#:1135-24-6 ferulic acid
CAS#:97-53-0 Eugenol CAS#:54509-73-8 ethene CAS#:46316-15-8 2-methoxy-4-vin... CAS#:2480-86-6 Apocynol
CAS#:97-54-1 Isoeugenol,mixt...
DownStream 10
CAS#:121-33-5 Vanillin CAS#:1206103-25-4 (3E)-4-(4-hydro... CAS#:751-38-2 1,2,3,4-TETRAPH... CAS#:2785-89-9 4-Ethyl-2-metho...
CAS#:7417-21-2 3,4-Dimethoxyph... CAS#:6380-23-0 3,4-Dimethoxy S... CAS#:55708-65-1 4-ethenyl-2-met... CAS#:64881-05-6 2-(3-methoxy-4-...
CAS#:77891-29-3 4-ethoxy-3-meth... CAS#:828269-23-4 tert-butyl-(4-e...

HS Code	2909500000
Summary	2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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p-Vinyl guaiacol

p-vinylguaiacol

MFCD00015437

3-06-00-04981 (Beilstein Handbook Reference)

o-Methoxy-p-vinylphenol

2-Methoxy-4-vinylphenol

Phenol, 2-methoxy-4-vinyl-

Phenol, 4-ethenyl-2-methoxy-

4-Hydroxy-3-methoxystyrene

2-Methoxy-4-ethenylphenol

EINECS 232-101-2

2-METHOXY-4-VINYL-PHENOL

3-Methoxy-4-hydroxystyrene

4-ETHENYL-2-METHOXYPHENOL

4-VINYLGUAIACOL

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 4-Hydroxy-3-methoxystyrene
Price: ￥2418.0/25g ￥848.0/5g ￥5548.0/100g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-Hydroxy-3-methoxystyrene
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 4-Hydroxy-3-methoxystyrene
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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