Sultamicillin

Modify Date: 2024-01-03 12:33:54

Sultamicillin Structure
Sultamicillin structure
Common Name Sultamicillin
CAS Number 76497-13-7 Molecular Weight 594.657
Density 1.6±0.1 g/cm3 Boiling Point 907.7±65.0 °C at 760 mmHg
Molecular Formula C25H30N4O9S2 Melting Point 190°
MSDS N/A Flash Point 502.8±34.3 °C

 Use of Sultamicillin


Sultamicillin is an orally active double prodrug of Ampicillin/Sulbactan. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with Ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant[1].

 Names

Name sultamicillin
Synonym More Synonyms

 Sultamicillin Biological Activity

Description Sultamicillin is an orally active double prodrug of Ampicillin/Sulbactan. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with Ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant[1].
Related Catalog
References

[1]. Friedel HA, et al. Sultamicillin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1989 Apr;37(4):491-522.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 907.7±65.0 °C at 760 mmHg
Melting Point 190°
Molecular Formula C25H30N4O9S2
Molecular Weight 594.657
Flash Point 502.8±34.3 °C
Exact Mass 594.145447
PSA 216.16000
LogP -0.29
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.668
Storage condition 2-8°C
Water Solubility Practically insoluble in water, very slightly soluble in methanol, practically insoluble in ethanol (96 per cent).

 Safety Information

HS Code 2934999090

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

6'-(2-Amino-2-phenylacetamido)penicillanoyloxymethylpenicillanate 1,1-dioxide
Sultancillin alkali
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, [[[(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl]carbonyl]oxy]methyl ester, 4,4-dioxide, (2S,5R)-
Unacid PD
SultaMcillin Base
VD 1827
1,1-Dioxopenicillanoyloxymethyl 6-(D-a-amino-a-phenylacetamido)penicillanate
({[(2S,5R,6R)-6-{[(2R)-2-Amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl]carbonyl}oxy)methyl (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide
Sultamicillin
Bethadl Orale
Sultamicillin Base
Baeimex
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