Kuwanon H

Modify Date: 2024-01-02 16:30:30

Kuwanon H Structure
Kuwanon H structure
Common Name Kuwanon H
CAS Number 76472-87-2 Molecular Weight 760.82400
Density 1.371g/cm3 Boiling Point 969.8ºC at 760 mmHg
Molecular Formula C45H44O11 Melting Point N/A
MSDS N/A Flash Point 292.5ºC

 Use of Kuwanon H


Kuwanon H is a flavonoid isolated from Morus bombycis, which acts as a potent non-peptide bombesin receptor antagonist. Kuwanon H selectively inhibits binding of gastrin releasing peptide CRP to GRP-preferring recepotr, with a Ki value of 290 nM in cells[1].

 Names

Name kuwanone H
Synonym More Synonyms

 Kuwanon H Biological Activity

Description Kuwanon H is a flavonoid isolated from Morus bombycis, which acts as a potent non-peptide bombesin receptor antagonist. Kuwanon H selectively inhibits binding of gastrin releasing peptide CRP to GRP-preferring recepotr, with a Ki value of 290 nM in cells[1].
Related Catalog
Target

Ki: 290 nM (GRP-preferring recepotr)[1]

References

[1]. Mihara S, et al. Non-peptide bombesin receptor antagonists, kuwanon G and H, isolated from mulberry. Biochem Biophys Res Commun. 1995 Aug 15;213(2):594-9.

 Chemical & Physical Properties

Density 1.371g/cm3
Boiling Point 969.8ºC at 760 mmHg
Molecular Formula C45H44O11
Molecular Weight 760.82400
Flash Point 292.5ºC
Exact Mass 760.28800
PSA 209.12000
LogP 8.83870
Index of Refraction 1.681
Water Solubility Insuluble (3.5E-6 g/L) (25 ºC)

 Synonyms

Albanin G
Alvanin G
kuwanon H
Moracenin A
NSC 356889