LB-60-OF61 hydrochloride

Modify Date: 2024-02-03 11:25:33

LB-60-OF61 hydrochloride structure	Common Name	LB-60-OF61 hydrochloride
	CAS Number	742064-38-6	Molecular Weight	531.05
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₃₁ClN₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LB-60-OF61 hydrochloride

LB-60-OF61 hydrochloride is a potent NAMPT (nicotinamide phosphoribosyltransferase) inhibitor. LB-60-OF61 hydrochloride is a cytotoxic compound with a selectivity towards MYC overexpressing cell lines[1].

Name	LB-60-OF61 hydrochloride

Description	LB-60-OF61 hydrochloride is a potent NAMPT (nicotinamide phosphoribosyltransferase) inhibitor. LB-60-OF61 hydrochloride is a cytotoxic compound with a selectivity towards MYC overexpressing cell lines[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Nampt
In Vitro	LB-60-OF61 is potent against HCT116 cells with an IC50 around 30 nM as measured in a 384 well format[1].
References	[1]. Estoppey D, et al. Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells. Sci Rep. 2017;7:42728. Published 2017 Feb 16.

Molecular Formula	C₂₉H₃₁ClN₆O₂
Molecular Weight	531.05