Piperazine-1,4-bis(2-hydroxypropanesulfonic acid) dihydrate

Modify Date: 2024-01-08 18:53:41

Piperazine-1,4-bis(2-hydroxypropanesulfonic acid) dihydrate Structure
Piperazine-1,4-bis(2-hydroxypropanesulfonic acid) dihydrate structure
 Common Name Piperazine-1,4-bis(2-hydroxypropanesulfonic acid) dihydrate
CAS Number 68189-43-5 Molecular Weight 362.420
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H22N2O8S2 Melting Point 320°C
MSDS N/A Flash Point N/A

 Use of Piperazine-1,4-bis(2-hydroxypropanesulfonic acid) dihydrate


POPSO is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC50 value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5[1][2][3].

 Names

Name Piperazine-1,4-bis(2-hydroxypropanesulfonic acid) dihydrate
Synonym More Synonyms

  Biological Activity

Description POPSO is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC50 value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5[1][2][3].
Related Catalog
References

[1]. Ng LT, et al. Effect of buffers and osmolality on anion uniport across the mitochondrial inner membrane. Biochim Biophys Acta. 1993 Jun 10;1143(1):29-37.

[2]. Vasconcelos, et al. Influence of zwitterionic pH buffers on the bioavailability and toxicity of copper to the alga Amphidinium carterae. 2009 Nov;19(10):2542-2550.

[3]. Kebede N, et al. Electrogenerated chemiluminescence of tris(2,2' bipyridine)ruthenium(II) using common biological buffers as co-reactant, pH buffer and supporting electrolyte. Analyst. 2015 Nov 7;140(21):7142-5.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Melting Point 320°C
Molecular Formula C10H22N2O8S2
Molecular Weight 362.420
Exact Mass 362.081757
PSA 172.44000
LogP -4.05
Index of Refraction 1.593
Storage condition Store at RT.
Water Solubility 1 M NaOH: 0.1 M, clear, colorless

 Safety Information

Hazard Codes T
Risk Phrases 21-23/24/25-25-36/37/38
Safety Phrases S22-S24/25
WGK Germany 3
HS Code 2933599090

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3,3'-Piperazine-1,4-diylbis(2-hydroxypropane-1-sulfonic acid)
MFCD00038350
3,3'-(1,4-Piperazinediyl)bis(2-hydroxy-1-propanesulfonic acid)
EINECS 269-199-1
2-hydroxy-3-[4-(2-hydroxy-3-sulfopropyl)piperazin-1-yl]propane-1-sulfonic acid
1,4-Piperazinedipropanesulfonic acid, β,β'-dihydroxy-
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Chemsrc provides CAS#:68189-43-5 MSDS, density, melting point, boiling point, structure, etc. Its name is Piperazine-1,4-bis(2-hydroxypropanesulfonic acid) dihydrate>> amp version: Piperazine-1,4-bis(2-hydroxypropanesulfonic acid) dihydrate

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