Esculentoside H

Modify Date: 2024-01-04 16:45:30

Esculentoside H structure	Common Name	Esculentoside H
	CAS Number	66656-92-6	Molecular Weight	989.104
	Density	1.5±0.1 g/cm3	Boiling Point	1042.8±65.0 °C at 760 mmHg
	Molecular Formula	C₄₈H₇₆O₂₁	Melting Point	N/A
	MSDS	N/A	Flash Point	295.3±27.8 °C

Use of Esculentoside H

Esculentoside H (EsH) is a water-soluble saponin isolated and purified from the root extract of perennial plant Phytolacca esculenta[1]. Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease[2].Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression[1].

Name	1-O-[(2β,3β,5ξ,18α)-3-{[4-O-(β-D-Glucopyranosyl)-β-D-xylopyranosyl]oxy}-2,23-dihydroxy-29-methoxy-28,29-dioxoolean-12-en-28-yl]-β-D-glucopyranose
Synonym	More Synonyms

Description	Esculentoside H (EsH) is a water-soluble saponin isolated and purified from the root extract of perennial plant Phytolacca esculenta[1]. Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease[2].Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> JNK
References	[1]. Ha SH, et al. Esculentoside H inhibits colon cancer cell migration and growth through suppression of MMP-9 gene expression via NF-kB signaling pathway. J Cell Biochem. 2019 Jun;120(6):9810-9819. [2]. Hu ZL, et al. Effect of esculentoside H on release of tumor necrosis factor from mouse peritoneal macrophages. Zhongguo Yao Li Xue Bao. 1993 Nov;14(6):550-2.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> MAPK/ERK Pathway >> JNK

References

[1]. Ha SH, et al. Esculentoside H inhibits colon cancer cell migration and growth through suppression of MMP-9 gene expression via NF-kB signaling pathway. J Cell Biochem. 2019 Jun;120(6):9810-9819.

[2]. Hu ZL, et al. Effect of esculentoside H on release of tumor necrosis factor from mouse peritoneal macrophages. Zhongguo Yao Li Xue Bao. 1993 Nov;14(6):550-2.

Density	1.5±0.1 g/cm3
Boiling Point	1042.8±65.0 °C at 760 mmHg
Molecular Formula	C₄₈H₇₆O₂₁
Molecular Weight	989.104
Flash Point	295.3±27.8 °C
Exact Mass	988.487915
LogP	1.78
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.635

β-D-Glucopyranose, 1-O-[(2β,3β,5ξ,18α)-3-[(4-O-β-D-glucopyranosyl-β-D-xylopyranosyl)oxy]-2,23-dihydroxy-29-methoxy-28,29-dioxoolean-12-en-28-yl]-

1-O-[(2β,3β,5ξ,18α)-3-{[4-O-(β-D-Glucopyranosyl)-β-D-xylopyranosyl]oxy}-2,23-dihydroxy-29-methoxy-28,29-dioxoolean-12-en-28-yl]-β-D-glucopyranose

Esculentoside H

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Esculentoside H
Price: ￥828.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

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