fenoxaprop-ethyl

Modify Date: 2024-01-02 19:01:54

fenoxaprop-ethyl Structure
fenoxaprop-ethyl structure
Common Name fenoxaprop-ethyl
CAS Number 66441-23-4 Molecular Weight 361.77600
Density 1.31g/cm3 Boiling Point 477.5ºC at 760mmHg
Molecular Formula C18H16ClNO5 Melting Point 84-85ºC
MSDS Chinese USA Flash Point 242.6ºC
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

 Names

Name fenoxaprop-ethyl
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.31g/cm3
Boiling Point 477.5ºC at 760mmHg
Melting Point 84-85ºC
Molecular Formula C18H16ClNO5
Molecular Weight 361.77600
Flash Point 242.6ºC
Exact Mass 361.07200
PSA 70.79000
LogP 4.60390
Index of Refraction 1.587
Storage condition -20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UA2454000
CHEMICAL NAME :
Propanoic acid, 2-(4-((6-chloro-2-benzoxazolyl)oxy)phenoxy)-, ethyl ester, (+-)-
CAS REGISTRY NUMBER :
66441-23-4
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C18-H16-Cl-N-O5
MOLECULAR WEIGHT :
361.80

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2357 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,373,1991
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>510 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S17,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,373,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
739 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,625,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4670 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,373,1991
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PBCWDF Proceedings of the British Crop Protection Conference - Weeds. (British Crop Protection Council, 2A Kidderminster Rd., Croydon, CRO 2UE, UK) 1976- Volume(issue)/page/year: -,11,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C136,1991
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
511 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C136,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
605 mg/kg/32D-C
TOXIC EFFECTS :
Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S17,1992
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1210 mg/kg/32D-C
TOXIC EFFECTS :
Liver - hepatitis (hepatocellular necrosis), diffuse Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S17,1992

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H317-H410
Precautionary Statements P273-P280-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi,N
Risk Phrases R43;R50/53
Safety Phrases S24;S37;S60;S61
RIDADR UN 3077 9/PG 3
RTECS UA2454000
HS Code 2934999023

 Synthetic Route

~85%

fenoxaprop-ethyl Structure

fenoxaprop-ethyl

CAS#:66441-23-4

Literature: Kalhor, Mehdi; Dadras, Akbar; Mobinikhaledi, Akbar; Tajik, Hassan Journal of the Chilean Chemical Society, 2011 , vol. 56, # 4 p. 833 - 836

~88%

fenoxaprop-ethyl Structure

fenoxaprop-ethyl

CAS#:66441-23-4

Literature: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY Patent: WO2004/2925 A2, 2004 ; Location in patent: Page 12 ;

~86%

fenoxaprop-ethyl Structure

fenoxaprop-ethyl

CAS#:66441-23-4

Literature: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY Patent: WO2004/2925 A2, 2004 ; Location in patent: Page 12 ;

~62%

fenoxaprop-ethyl Structure

fenoxaprop-ethyl

CAS#:66441-23-4

Literature: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY Patent: WO2004/2925 A2, 2004 ; Location in patent: Page 19 ;

~91%

fenoxaprop-ethyl Structure

fenoxaprop-ethyl

CAS#:66441-23-4

Literature: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY Patent: WO2004/2925 A2, 2004 ; Location in patent: Page 11 ;

 Customs

HS Code 2934999023
Summary 2934999023 2,8,9-trioxa-5-aza-1-silabicyclo[3.3.3]undecane。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

 Articles25

More Articles
Effect of herbicides on glutathione S-transferases in the earthworm, Eisenia fetida.

Environ. Sci. Pollut. Res. Int. 15(2) , 143-9, (2008)

Earthworms have been studied as a readily available, easily maintainable and cheap test species for assessing chemical pollution, and may be an alternative to in vivo rodent bioassays. The current inv...

Chiral separation of three agrochemical toxins enantiomers by high-performance liquid chromatography on a vancomycin crystalline degradation products-chiral stationary phase.

Biomed. Chromatogr. 21(3) , 234-40, (2007)

This work aims to evaluate for the enantiomeric separations of three agrochemical toxins: haloxyfop-methyl, fenoxaprop-p-ethyl and indoxacarb on crystalline degradation products-chiral stationary phas...

Persistence of herbicide fenoxaprop ethyl and its acid metabolite in soil and wheat crop under Indian tropical conditions.

J. Environ. Sci. Health B 48(5) , 324-30, (2013)

The persistence of fenoxaprop ethyl {Ethyl (RS)-2-[4-(6-chloro-1,3-benzoxazol-2-yloxy) phenoxy] propionate} herbicide and its active metabolite fenoxaprop acid was investigated in soil and wheat crop....

 Synonyms

Ethyl 2-{4-[(6-chlorobenzoxazol-2-yl)oxy]phenoxy}propionate
ethyl (RS)-2-[4-(6-chloro-1,3-benzoxazol-2-yloxy)phenoxy]propionate
ethyl 2-[4-[(6-chloro-2-benzoxazolyl)oxy]phenoxy]propanoate
EINECS 266-362-9
MFCD00078610
rac-ethyl (2R)-2-{4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy}propanoate
ethyl (RS)-2-[4-(6-chlorobenzoxazol-2-yloxy)phenoxy]propionate
Fenoxaprop-ethyl