Gomisin J
Modify Date: 2024-01-02 12:57:26
Gomisin J structure
|
Common Name | Gomisin J | ||
|---|---|---|---|---|
| CAS Number | 66280-25-9 | Molecular Weight | 388.454 | |
| Density | 1.161 | Boiling Point | 587.5±50.0 °C at 760 mmHg | |
| Molecular Formula | C22H28O6 | Melting Point | 148-149 ºC | |
| MSDS | N/A | Flash Point | 309.1±30.1 °C | |
Use of Gomisin JGomisin J is a small molecular weight lignan found in Schisandra chinensis and has been demonstrated to have vasodilatory activity[1]. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK, LKB1 and Ca2+/calmodulin-dependent protein kinase II and inhibition of fetuin-A in HepG2 cells. gomisin J has potential benefits in treating nonalcoholic fatty liver disease[2]. |
| Name | Gomisin J |
|---|---|
| Synonym | More Synonyms |
| Description | Gomisin J is a small molecular weight lignan found in Schisandra chinensis and has been demonstrated to have vasodilatory activity[1]. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK, LKB1 and Ca2+/calmodulin-dependent protein kinase II and inhibition of fetuin-A in HepG2 cells. gomisin J has potential benefits in treating nonalcoholic fatty liver disease[2]. |
|---|---|
| Related Catalog | |
| Target |
AMPK Ca2+ |
| References |
| Density | 1.161 |
|---|---|
| Boiling Point | 587.5±50.0 °C at 760 mmHg |
| Melting Point | 148-149 ºC |
| Molecular Formula | C22H28O6 |
| Molecular Weight | 388.454 |
| Flash Point | 309.1±30.1 °C |
| Exact Mass | 388.188599 |
| PSA | 77.38000 |
| LogP | 4.80 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.556 |
| Hazard Codes | Xi |
|---|
|
~%
Gomisin J CAS#:66280-25-9 |
| Literature: Tanaka, Masahide; Ohshima, Toshihiro; Mitsuhashi, Hiroshi; Maruno, Masao; Wakamatsu, Takeshi Tetrahedron, 1995 , vol. 51, # 43 p. 11693 - 11702 |
|
~%
Gomisin J CAS#:66280-25-9 |
| Literature: Tanaka, Masahide; Ohshima, Toshihiro; Mitsuhashi, Hiroshi; Maruno, Masao; Wakamatsu, Takeshi Tetrahedron, 1995 , vol. 51, # 43 p. 11693 - 11702 |
![(3aS,R-Biar)-3a,4-dihydro-6,7,8,9,10,11-hexamethoxydibenzo[4,5:6,7]cycloocta[1,2-c]furan-1(3H)-one structure](https://www.chemsrc.com/caspic/384/110397-81-4.png)
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| Dibenzo[a,c]cyclooctene-3,10-diol, 5,6,7,8-tetrahydro-1,2,11,12-tetramethoxy-6,7-dimethyl-, (6R,7S)- |
| (-)-gomisin J |
| (6R,7S)-1,2,11,12-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulene-3,10-diol |
| UNII:X13A57600T |
| 6(S),7(R)-Dibenzo(a,c)cyclooctene-3,10-diol,5,6,7,8-tetrahydro-1,2,11,12-tetramethoxy-6,7-dimethyl |
| Dibenzo(a,c)cyclooctene-3,10-diol,5,6,7,8-tetrahydro-1,2,11,12-tetramethoxy-6,7-dimethyl-,stereoisomer |
- BioBioPha
- China
- Product Name: Gomisin J
- Price: ￥Inquiry/10mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Gomisin J
- Price: ￥4000.0/5mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Gomisin J
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
Get all suppliers and price by the below link: