atracurium besylate
Modify Date: 2024-01-02 14:08:48
atracurium besylate structure
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Common Name | atracurium besylate | ||
|---|---|---|---|---|
| CAS Number | 64228-81-5 | Molecular Weight | 1243.479 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C65H82N2O18S2 | Melting Point | 85-90ºC | |
| MSDS | N/A | Flash Point | N/A | |
Use of atracurium besylateAtracurium Besylate is a neuromuscular blocking agent with ED95 of 0.2 mg/kg. Target: nAChRAtracurium besylate is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Atracurium is classified as an intermediate-duration non-depolarizing neuromuscular-blocking agent [1]. A 14C radiolabeled metabolism study in cats confirmed the lack of hepatic or renal involvement in the metabolism of atracurium: radioactivity eliminated in bile and urine was predominantly from metabolites rather than the unchanged parent drug [2]. |
| Name | atracurium besylate |
|---|---|
| Synonym | More Synonyms |
| Description | Atracurium Besylate is a neuromuscular blocking agent with ED95 of 0.2 mg/kg. Target: nAChRAtracurium besylate is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Atracurium is classified as an intermediate-duration non-depolarizing neuromuscular-blocking agent [1]. A 14C radiolabeled metabolism study in cats confirmed the lack of hepatic or renal involvement in the metabolism of atracurium: radioactivity eliminated in bile and urine was predominantly from metabolites rather than the unchanged parent drug [2]. |
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| Related Catalog | |
| References |
| Melting Point | 85-90ºC |
|---|---|
| Molecular Formula | C65H82N2O18S2 |
| Molecular Weight | 1243.479 |
| Exact Mass | 1242.500366 |
| PSA | 257.60000 |
| LogP | 11.32610 |
| Storage condition | 2-8°C |
| Water Solubility | H2O: ~27 mg/mL |
| RIDADR | NONH for all modes of transport |
|---|---|
| WGK Germany | 3 |
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~86%
atracurium besylate CAS#:64228-81-5 |
| Literature: Stenlake; Waigh; Dewar; et al. European Journal of Medicinal Chemistry, 1981 , vol. 16, # 6 p. 515 - 524 |
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atracurium besylate CAS#:64228-81-5 |
| Literature: European Journal of Medicinal Chemistry, , vol. 16, # 6 p. 515 - 524 |
|
~%
atracurium besylate CAS#:64228-81-5 |
| Literature: European Journal of Medicinal Chemistry, , vol. 16, # 6 p. 515 - 524 |
|
~%
atracurium besylate CAS#:64228-81-5 |
| Literature: European Journal of Medicinal Chemistry, , vol. 16, # 6 p. 515 - 524 |
|
~%
atracurium besylate CAS#:64228-81-5 |
| Literature: European Journal of Medicinal Chemistry, , vol. 16, # 6 p. 515 - 524 |
|
~%
atracurium besylate CAS#:64228-81-5 |
| Literature: European Journal of Medicinal Chemistry, , vol. 16, # 6 p. 515 - 524 |
![1-[(3,4-Dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline structure](https://www.chemsrc.com/caspic/235/6957-27-3.png)
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| NIMBEX |
| bisbenzènesulfonate de 2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-diméthoxybenzyl)-6,7-diméthoxy-2-méthyl-1,2,3,4-tétrahydroisoquinoléinium] |
| 2,2'-{1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] bisbenzenesulfonate |
| MFCD00797403 |
| 2,2'-{Pentan-1,5-diylbis[oxy(3-oxopropan-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisochinolinium]bisbenzolsulfonat |
| 2,2'-{Pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] bisbenzenesulfonate |
| atracurium besylate |
| atracurium besilate [INN_en] |
| 2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-{[3,4-bis(methyloxy)phenyl]methyl}-2-methyl-6,7-bis(methyloxy)-1,2,3,4-tetrahydroisoquinolinium] bisbenzenesulfonate |
| EINECS 264-743-4 |
| Atracurium Besylate Cisatracurium |
| Isoquinolinium, 2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl- benzenesulfonate (1:2) |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: atracurium besylate
- Price: ￥398.0/250mg ￥1008.0/1g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Atracurium besylate
- Price: $250.0/100mg $500.0/250mg $1000.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Atracurium besylate
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: atracurium besylate
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
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