Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate

Modify Date: 2024-01-06 09:12:54

Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate Structure
Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate structure
Common Name Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate
CAS Number 632-93-9 Molecular Weight 267.32
Density 1.12g/cm3 Boiling Point 335ºC at 760 mmHg
Molecular Formula C14H21NO4 Melting Point 130-132 °C(lit.)
MSDS Chinese USA Flash Point 123.3ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate


Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate is a mouse-modeling drug that can induce Mallory body (MB) formation. MBs reached maximum concentration on day 5 of refeeding. Liver cell regeneration increased on the third day of refeeding[1].

 Names

Name 3,5-diethoxycarbonyl-1,4-dihydrocollidine
Synonym More Synonyms

  Biological Activity

Description Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate is a mouse-modeling drug that can induce Mallory body (MB) formation. MBs reached maximum concentration on day 5 of refeeding. Liver cell regeneration increased on the third day of refeeding[1].
Related Catalog
References

[1]. Q X Yuan, et,al. Mallory body induction in drug-primed mouse liver. Hepatology. 1996, 24, 3.  

 Chemical & Physical Properties

Density 1.12g/cm3
Boiling Point 335ºC at 760 mmHg
Melting Point 130-132 °C(lit.)
Molecular Formula C14H21NO4
Molecular Weight 267.32
Flash Point 123.3ºC
Exact Mass 267.14700
PSA 64.63000
LogP 2.22870
Index of Refraction 1.51
Storage condition Flammables area

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933399090

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate
EINECS 211-188-0
3,5-Diethoxycarbonyl-1,4-dihydro-2,4,6-collidine
MFCD00005950
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